Lecture 9 Flashcards
(33 cards)
hypothalamus
control of hormone secretion
pineal gland
reproductive maturation, body rhythms
anterior pituitary
hormone secretion by thyroid, adrenal cortex, gonads, growth
posterior pituitary
water balance, salt balance
thyroid
growth and development, metabolic rate
adrenal cortex
salt and carb metabolism, inflammatory reactions
adrenal medulla
emotional arousal
pancreas
sugar metabolism
gut
digestion and appetite control
gonads
body development, maintenance of reproductive organs in adults
Berthold’s classical experiment with roosters
group 1: left undisturbed
group 2: testes removed
group 3: testes removed and replaced in abdomen
group 1 formed large comb/wattles, mounted hens, was aggressive, and had normal crowning
group 2 formed small comb/wattles, didn’t mount hens, wasn’t aggressive, and had weak crowning
group 3 formed large comb/wattles, mounted hens, was aggressive, and had normal crowning
conclusion: testes release a chemical signal (hormone) that has widespread effects
canary example
gave female canaries testosterone, after one week started to sing, but stopped when weren’t given anymore testosterone
autocrine
affects self
paracrine
local diffusion
pheromone function
same species
allomone function
other species
neuroendocrine cell actions
blend neuronal and endocrine signal mechanisms
neuron acting on another neuron, in second neuron action potential causes a hormone to be released into blood stream to affect target cells
general principle of hormone systems
pulsatile (burst) secretion
hormonal effects depends on target system having receptors
some hormones affect more than one target
some targets are affected by more than one hormone
Neuronal vs hormonal communication
neuronal com: directed, restricted to specific targets (telephone) fast (milliseconds) APs, all or none hormonal com: widespread can affect many targets (TV) slow (seconds or minutes or longer) hormonal signals graded
how are hormones classified:
protein, amine, and steriod
classified by chemical structure
protein- amino acid chain
amine- single amino acid
steroid- carbon rings
protein hormone action
need a channel
rapid, short lived (min-hours)
steroid hormone action
always to go through membrane long lasting (hours days)
autocrine feedback loop
endocrine cells to target cells back to negative feedback
target cell feedback
endocrine cells to target cells to biological response then negative feedback