Lecture 9 - Anemia, Anti-arrhythmics, Hemostasis

Question 1

What class of anti-arrhythmic drugs is a Na+ channels blocker, and decreases excitability and conduction velocity?

Answer 1

Class 1 Anti-arrhythmic Drugs

Question 2

Which class of drugs slows the rate of rise of the O Phase, which increases effective refractory period.

Answer 2

Class 1A Anti-arrhythmic Drugs

Question 3

What are the three Class 1A anti-arrhythmia agents?

Answer 3

1. Quinidine
2. Procainamide (Pronestyl)
3. Disopiramide (Norpace)

Question 4

Hemostasis requires what three factors to occur?

Answer 4

1) adequate number of platelets,
2) the platelets are functional
3) coagulation cascade (for fibrin production, the glue..)

Question 5

When does hemostasis begin?

Answer 5

When there is damage to the normal healthy tissue, it maintains a balance and blocks unwanted activation and clot formation.

Question 6

What effect does prostacyclins have on platelets?

Answer 6

They bind to platelet membrane receptors cAMP and inhibits de-granulation