Lecture 9: Cell Transport (part 1) Flashcards
What contributes to the permeability of the cell membrane?
both the lipid bilayer and the transporters present
What is selective permeability?
Some substances can penetrate the membrane while others cannot.
Do all cells have the same permeabilty?
no
What are the transport mechanisms for transport of substances in and out of the cell?
Membrane Transport
On which membrane transport mechanisms used depend on?
1) the physical properties of the substance
2) whether the process is spontaneous or non-spontaneous.
What are the three “levels” of the permeability of substances?
A. Can not cross the membrane at all.
B. Can cross the phospholipid bilayer directly.
C. Need help from transporters.
What are transporters?
transmembrane proteins
What do transporters do?
Help substances that can’t cross the phospholipid bilayer.
How specific are transporters?
- A transporter is specific for the substance(s) it allows to pass.
- Cells in the body will have different transporters leading to specific permeability characteristics.
What are the 5 types of membrane transport?
- Simple diffusion
- Facilitated diffusion
- Osmosis
- Active transport
- Bulk Transport
For Simple diffusion:
- Transport via?
- Energy required from cell?
- For which types of substances?
lipid bilayer
No
Small and/or hydrophobic (non-poplar)
For Facilitated diffusion:
- Transport via?
- Energy required from cell?
- For which types of substances?
transporters
No
Large and/or hydrophilic (polar), ions (charged atoms/molecules)
For Osmosis:
- Transport via?
- Energy required from cell?
- For which types of substances?
lipid bilayer (but mainly transporters)
No
Water
For Active transport:
- Transport via?
- Energy required from cell?
- For which types of substances?
transporters
Yes
Large and/or hydrophilic
For Bulk transport:
- Transport via?
- Energy required from cell?
- For which types of substances?
vesicles
Yes
Very large in large amounts
What are the two passive type of transport?
diffusion and osmosis
What is passive transport?
mechanisms used by the cell to transport substances across the membrane that don’t require energy.
Why can passive transport mechanisms not require energy?
they are driven by concentration gradients
What is a gradient?
What is a concentration gradient?
- A gradient is a gradual difference in a variable in one area compared to an adjacent area.
- A difference in solute concentrations in a solution creates a concentration gradient.
In biology, what areas have concentration gradients?
the inside and outside of the cell that are separated by the cell membrane.
Describe the motions of molecules:
_________ motion
_________ direction of motion
And collisions or the molecules:
*
*
constant motion
random direction of motion
And collisions of the molecules:
*Molecules can collide and bounce off each other and other matter which changes the direction of motion of these molecules
*Collisions influence the diffusion of substances.
If a concentration gradient exists, the net movement of a substance will proceed in which direction?
from the area of high concentration to low concentration.
Does diffusion stop?
*Diffusion will continue until there is no more concentration gradient producing equilibrium.
*In equilibrium, molecules are still moving randomly but there is no more net movement of the substance.
How do concentration gradients work in the presence of many substances?
Diffusion of a substance is based on its concentration gradient and not affected by another substance.