Lecture 9 - Neuropsychology Flashcards

(27 cards)

1
Q

what is neuropsychology

A
  • Study of behaviours with reference to their neurobiological bases
  • Neuropsychology draws from many fields including anatomy, biology, ethology, pharmacology, physiology, and philosophy
  • Focus is on the links between brain & behaviour
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2
Q

Cognitive neuropsychology

A

academic discipline: research into the biological bases of cognition, emotions, and/or actions.

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3
Q

clincial neuropsychology

A

an applied science: the behavioural expression of brain dysfunction.

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4
Q

Neurospychology vs clincial psychology

A
  • Clinical Psychology
    o Assessment, diagnosis, and treatment of “psychological and mental health problems”.
     vs
  • Clinical Neuropsychology
    o Assessment, diagnosis, and treatment of “psychological disorders associated with conditions affecting the brain”.
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5
Q

neurospychology models

A

Historical:
- gall and phrenology
- broca and tan

modern:
- modular organisation
- lesion studeis
-neuropsycholoigcal assessment

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6
Q

gall and phrenology

A
  • Personality traits and characteristics can be localised
  • If you use a part more, it gets bigger
  • Bigger parts of the brain will cause bumps on the skull
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7
Q

broca and tan

A
  • Neurophysiology of language
  • Studied people with “ahasia”, performed autopsies and identified “Broca’s Area”
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8
Q

modular organisation

A

– Specific brain regions are necessary but not sufficient for complex mental tasks
– Mental processes are the result of many component processes (cognitive or sensory), specific brain regions are responsible for component processes.
– Complex mental processes are an “emergent property” of the co-ordinated activity of many brain regions
– A specific brain region can contribute to many mental processes

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9
Q

lesion studies

A

Behavioural consequences of brain changes
– Tumour
– Stroke
– Epilepsy
– Traumatic brain injury
– Transcranial magnetic stimulation

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10
Q

neuropsychological assessment

A

– Psychometric tests
– Medical history/tests
– Clinical interview
– Psychosocial history
“which brain region, or combination of regions is/are impaired?” (localisation of function)

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11
Q

mechanisms of brain dysfunction

A

cerebrovascular accidents
trumatic brain injury
neurodegenerative diseases

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12
Q

what is a cerebrovascualr accident

A

stroke
Loss of blood supply to parts of the brain

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13
Q

types of cerebrovascular accidents

A

cerebral ischemia
- hypoxia & infranction
- or transient ischemic attack

haemorrage
- intracranial bleeding
-compress surroudnign tissue

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14
Q

recovery of stroke depends on what

A

from Storke
- Severity and location of initial injury
- Quality and speed of medical intervention
- Health of remaining tissue
- Degree to which remaining nervous system can reorganise

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15
Q

trumatic brian injuries what is it

A

Caused by sudden impact to the brain.
trauma occurs because the brain floats in cerebrospinal fluid

  • Following the impact, the brain shifts in the skull, bumping against bone and damaging nerve fibres
  • The amount of damage depends on the amount of force involved in trauma
  • Damage is often more widespread than with stroke and harder to pinpoint.
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16
Q

primary injuries

A
  • skull fracture and shifting intracranial contents
  • tearing, stretching, bruising, bleeding and swelling
  • acceleration or deceleration forces result in a combination of
    o Translation (linear, stretches the nerve fibres (axons)
    o Rotation (greater strain on the nerve fibres (axons))
17
Q

neurodegnerative diseases - dementia

A

DSM 5 “Major Neurocognitive Disorder”: “significant” decline in one or more of the domains of:
- Complex attention
- Executive function
- Learning and memory
- Language
- Perceptual motor ability
- Social cognition

18
Q

Gradual cell death “atrophy”

A

Gradual cell death “atrophy”
Each neurodegenerative disease affects a particular type of brain cell or cells in a particular part of the brain; causing them to be the first to stop working:
- The symptoms can usually be identified by tests
- Clinical history can revel onset and progression
- Can lead to significant diagnoses

19
Q

modular appraoach to neurodegenerative diseases

A
  • Use tests and clinical interview to investigate mental processes and subprocesses to identify which are impaired
  • Infer which brain regions or systems are implicated (“localisation of function”)
20
Q

perceptial distrubances - nuerodegenerative diseoders

A
  • Impairment in ability to organise, recognise, interpret and make sense of incoming sensory information
  • Visual: eyes to the thalamus, then to particular areas do the occipital love of the cerebral cortex then along two separate pathways where specialised analyses occur that result in difference visual perceptions
21
Q

“what” pathway

A
  • Visual agnosia: Inability to identify objects by their appearance but can still see, describe and draw objects
  • Prosopagnosia: inability to recognise faces
22
Q

“where” pathway

A
  • Hemineglect: difficulty seeing, responsible to or acting or information coming from one side of space (incl their own body)
  • Appears to be an attentional disturbance rather than a purely sensory/perceptual disturbance
23
Q

“apraxia”

A

movement disorders

24
Q

movement disroders

A
  • Impairment in the ability to perform or coordinate previously intact motor skills
  • Ideational apraxia: individual movements needed to perform a task are all correctly executed but in the wrong order
  • Ideomotor apraxia: difficulties in performing the skilled movements of a task
25
alzhimers disease
- Low CSG amyloid beta and high tau - Deficit of the neurotransmitter acetylcholine (Ach) - Neurodegenerative atrophy – hippocampal and cerebral cortex  Memory deficits (consolidation & storage, “rapid forgetting”)  Executive dysfunction (judgment & planning)  Language impairment  Global deficits (Apraxia, aphasia, agnosia)
26
vascular dementia
- 2nd most common dementia - Prevalence: 1-4% of people aged over 65 years (increases with increasing age) - Cognitive changes \ Pattern of deficits is a direct effect of regions impacted by vascular compromise Typically, abrupt onset followed by stepwise decline
27
parkinson's disease
- Parkinsonism, “bradykinesia, in combination with at least 1 or rest tremor or rigidity” - Bradykinesia: slowed movements AND decrement in amplitude or speed - Rigidity: resistance to passive movement - Rest tremor: refers to a 4- to 6-Hz tremor in the fully resting limb, which is supressed during movement initiation - Cognitive impairment: approx. 25% develop PD-MCI Often converts to PDD: prominent executive dysfunction