Lecture 9 - Sleep And Physical Health Flashcards Preview

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Flashcards in Lecture 9 - Sleep And Physical Health Deck (10)
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1
Q

Obesity and diabetes

A

Obese adults are five times more likely to be diagnosed with diabetes

2
Q

Sleeping less over years

A

1913 - 10.5 hrs

1994 - 7.7 hrs

3
Q

Heart disease in sleep deprived nurses

A

Sleep durations were associated with risk of coronary heart disease during 10 year follow up

4
Q

Sleep and diabetes

A

Epidemiological study; Sleep durations less than 6 or more hours associated with an increase prevalence of diabetes and impaired glucose tolerance
Sleeping less than 6hr increases diabetes by 30%
Short and long sleep associated with insulin resistance in women
Short and long sleep durations increases risk of diabetes in men
Regularity of naps increases risk of diabetes and increases fasting blood glucose (if above average can be a marker of diabetes)

5
Q

Sleep and obesity in adults

A

50 epidemiological studies in different geographical regions found significant association between short sleep - less than 6 hours and increased obesity risk

6
Q

Sleep and obesity in children

A

Short sleep duration at 3yoa is a significant predictor if childhood obesity
Also seen in Japanese children
- in adolescents every hour of sleep reduces risk of obesity by 80%

7
Q

Sleep and mortality

A

Best survival = 7hrs

15% risk of mortality with sleep more than 8.5 or less than 4 hours

8
Q

Obesity and heart failure

A

Obesity doubles risk

9
Q

Sleep and the cold

A

3 times More likely to get cold from nasal drops containing rhinovirus if had less than 7 hrs sleep

10
Q

HPA axis

A

Hypothalamo-pituitary-adrenal axis
Mediates stress response
Stressful stimuli lead to release of corticotropin- releasing hormone from the hypothalamus
This results in release of adrenocorticotropic (ACTH) hormone from the pituitary
This leads to release of cortisol from the adrenal gland
- sleep is initiated when cortisol is low
- SWS has inhibitory effect is HPA axis activity
- HPA hyperactivity may underlie insomnia and depression