Lecture case study notes - week 2

Question 1

Rate of reaction

Answer 1

Average rate= change in product/ change in time =deltaP/t
Measured in Ms^-1

Question 2

What determines the rate of reaction

Answer 2

Concentraction
Catalyst

Temperature
Pressure
PH
Collisions etc.

Question 3

Pseudo First order reactions

Answer 3

Second order reactions:
A+B—>with K to P
(Rate constant k)

Rate of reaciton:
V-k(A)(B)

Units of k: M-1s-1

But if A»B or B»A reaction is pseudo first order

Question 4

What will happen to rate of reaction over time

Answer 4

• will decrease: reactants will be used up, products will increase - equilibrium

Question 5

Why is never all of the reactants used up but graph comes into equilibrium

Answer 5

Versable reactions

Question 6

What is V0?

Answer 6

V0 is the initial (Fastest) rate of reaction

At a fixed conc of enzyme increasing substrate increases reaction rate

Question 7

Kcat

Answer 7

K2 - enzymeʻs turnover into catalytic power
- max nr of substrate mols converted into porduct by an enzyme mol in unit time

Question 8

Km

Answer 8

• dependws on pH, temp