lecture one Flashcards

(26 cards)

1
Q

in reotrovirus ife cycle, which is the complete form? which forms have LTR?

A

linear form, linear and provirus

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2
Q

name functions for gag, env, and pol

A

internal packaging, outer packaging, enzymes and proteins

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3
Q

what is structure of LTR?

A

U3-R-U5

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4
Q

how many bp repeat of target DNA

A

4-6

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5
Q

what does tRNA primer for?

A

synthesis of minus strand

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6
Q

which jump is this? : ss DNA R region pair with 3’ terminus to another retroviral RNA?

A

first

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7
Q

in minus strand synthesis which end is degraded?

A

5”

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8
Q

tRNA primes first strand synthesis by __________

A

RT

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9
Q

which jump: positive DNA jumps to other end of negative?

A

second

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10
Q

during intgration which end is recessed?

A

3”

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11
Q

in integrase which is conserved in these terminal IRs. cut made on other side?

A

CA

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12
Q

where is promoter found?

A

U3

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13
Q

V-onc proteins are initially expressed as _______ proteins

A

gag fusion proteins

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14
Q

helper virus suppled what

A

missing functions

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15
Q

replication-defective viruses are generated by what

A

deletion in the proviurs

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16
Q

packaged with wt virus RNA and recombination occurs to what?

17
Q

explain two parts of TY and how get it

A

A-gag related
B-pol related
frameshift

18
Q

what has ds DNA?

19
Q

examples of LTR retrotransposons, what do they encode

A

TY and Copia,RT and integreas

20
Q

LINES derived from what

21
Q

what encodes revers transcriptase, nucleic acid binding protein, and endonuclease?

A

non-ltr retro

22
Q

sines derived from what

23
Q

LTR retro has RNA pol ____ promoter

24
Q

what are cis acting? propagation of what

A

lines, functional elements

25
what has ORF and what do 1 and 2 stand for?
Lines, 1=DNA binding protein. 2= RT endonuclease
26
most abundant in human genome? retroelemts are what percent of human genome?
LINES, 40