Lecture35: Hypertension Flashcards
What is the diastolic limit for Hypertension diagnosis?
90
What is the systolic limit for hypertension diagnosis?
140
Which vessel has increased resistance in hypertension?
Arterioles
What is hypertension a risk factor for the development of?
Atherosclerosis
In which vessels does the thickening of the media layer occur?
Arterioles and small arteries
What is the media layer thickening a result of?
Smooth muscles hyperplasia and collagen deposition
What is Hyaline Arteriosclerosis associated with?
Benign Hypertension
What is a characteristic of Hyaline Arteriosclerosis?
Luminal Narrowing, pink hyaline thickening
Where do the plasma components leak into from?
Injured ECs
In kidneys, what do the arterial narrowing caused by Hyaline Arteriosclerosis lead to?
Nephrosclerosis, which leads to renal failure
What happens in the kidney when it has nephrosclerosis?
The nephrons are lost, thus leading to chronic renal failure that then exacerbates the hypertension
What enzyme does the kidney produce?
Renin
What does the adrenal cortex produce?
Aldosterone
What characterizes Hyperplastic Arteriosclerosis?
Onion skin
What is a symptom exclusive to malignant hypertension Hyperplastic Arteriolosclerosis?
Necrotizing Arteriolitis
