Leprosy

Question 1

What is the primary causative agent of leprosy?

Answer 1

Mycobacterium leprae

Question 2

True or False: Leprosy is primarily spread through respiratory droplets.

Answer 2

True

Question 3

Which class of antibiotics is primarily used to treat leprosy?

Answer 3

Multidrug therapy (MDT) including rifampicin, dapsone, and clofazimine

Question 4

What is the mechanism of action of rifampicin?

Answer 4

Inhibition of bacterial RNA synthesis

Question 5

Fill in the blank: Dapsone is a _______ antibiotic.

Answer 5

sulfonamide

Question 6

What is the role of clofazimine in leprosy treatment?

Answer 6

It acts as an antimicrobial and anti-inflammatory agent.

Question 7

True or False: Leprosy can be completely cured with appropriate treatment.

Answer 7

True

Question 8

What is the duration of treatment for leprosy with multidrug therapy?

Answer 8

6 months to 2 years, depending on the form of leprosy

Question 9

Which drug is known to cause a reddish-brown discoloration of the skin?

Answer 9

Clofazimine

Question 10

What adverse effect is associated with dapsone?

Answer 10

Hemolytic anemia

Question 11

What is the standard treatment regimen for multibacillary leprosy?

Answer 11

Rifampicin, dapsone, and clofazimine for 12 months

Question 12

True or False: Leprosy is a highly contagious disease.

Answer 12

False

Question 13

What is the primary goal of leprosy treatment?

Answer 13

To kill the Mycobacterium leprae and prevent disability

Question 14

Fill in the blank: The World Health Organization recommends _______ therapy for leprosy.

Answer 14

multidrug

Question 15

What type of leprosy is characterized by a low bacterial load?

Answer 15

Tuberculoid leprosy

Question 16

What is the primary method of diagnosing leprosy?

Answer 16

Clinical examination and skin smear or biopsy

Question 17

Which drug is contraindicated in patients with G6PD deficiency?

Answer 17

Dapsone

Question 18

What is the significance of the lepromin test?

Answer 18

It helps to determine the immune response to Mycobacterium leprae.

Question 19

True or False: Clofazimine is effective against other mycobacterial infections.

Answer 19

True

Question 20

What is the main side effect of rifampicin?

Answer 20

Hepatotoxicity

Question 21

What is the recommended treatment for a leprosy patient with a severe reaction?

Answer 21

Corticosteroids

Question 22

Fill in the blank: Leprosy primarily affects the _______ and _______ system.

Answer 22

skin, peripheral nervous

Question 23

What is the consequence of untreated leprosy?

Answer 23

Disability and deformities

Question 24

Which population is most at risk for developing leprosy?

Answer 24

Those with close, prolonged contact with infected individuals

Question 25

What is the purpose of contact tracing in leprosy management?

Answer 25

To identify and treat individuals who may have been exposed to the disease.

Question 26

True or False: Leprosy is a disease of the past and no longer occurs.

Answer 26

False

Question 27

What is the role of the skin smear test in leprosy diagnosis?

Answer 27

To detect the presence of Mycobacterium leprae.