Tuberculosis

Question 1

What is the primary causative agent of tuberculosis?

Answer 1

Mycobacterium tuberculosis

Question 2

True or False: Tuberculosis can be spread through the air.

Answer 2

True

Question 3

Name the first-line drug commonly used to treat tuberculosis.

Answer 3

Isoniazid

Question 4

Fill in the blank: The combination of Isoniazid and __________ is often used in tuberculosis treatment.

Answer 4

Rifampicin

Question 5

What is the mechanism of action of Rifampicin?

Answer 5

Inhibition of bacterial RNA polymerase

Question 6

Which drug is known to cause liver toxicity in tuberculosis treatment?

Answer 6

Isoniazid

Question 7

What is the standard duration of treatment for drug-susceptible tuberculosis?

Answer 7

6 months

Question 8

True or False: Ethambutol is effective against drug-resistant strains of Mycobacterium tuberculosis.

Answer 8

False

Question 9

What is the role of Pyrazinamide in tuberculosis therapy?

Answer 9

To kill dormant bacteria in acidic environments

Question 10

Which vitamin is often prescribed to counteract the side effects of Isoniazid?

Answer 10

Vitamin B6 (Pyridoxine)

Question 11

Name a second-line drug used for multidrug-resistant tuberculosis.

Answer 11

Ciprofloxacin

Question 12

What is the primary target of Isoniazid in Mycobacterium tuberculosis?

Answer 12

Mycolic acid synthesis

Question 13

Fill in the blank: The Directly Observed Treatment, Short-course (DOTS) strategy is used to ensure __________ adherence.

Answer 13

treatment

Question 14

What type of bacteria is Mycobacterium tuberculosis classified as?

Answer 14

Acid-fast bacillus

Question 15

True or False: Rifampicin can interact with oral contraceptives, reducing their effectiveness.

Answer 15

True

Question 16

What is the most common side effect of Ethambutol?

Answer 16

Optic neuritis

Question 17

Which drug can cause red-orange discoloration of urine and tears?

Answer 17

Rifampicin

Question 18

What is the role of Streptomycin in tuberculosis treatment?

Answer 18

It is an aminoglycoside antibiotic used for drug-resistant cases.

Question 19

What is the primary reason for the development of drug resistance in tuberculosis?

Answer 19

Inadequate treatment and non-adherence to therapy

Question 20

Fill in the blank: The __________ test is used to determine the susceptibility of Mycobacterium tuberculosis to antibiotics.

Answer 20

sensitivity

Question 21

Name a common adverse effect of Pyrazinamide.

Answer 21

Hyperuricemia

Question 22

What is the recommended initial regimen for drug-sensitive tuberculosis?

Answer 22

Isoniazid, Rifampicin, Pyrazinamide, and Ethambutol

Question 23

True or False: Tuberculosis treatment should be continued even if symptoms improve.

Answer 23

True

Question 24

What is the function of the BCG vaccine?

Answer 24

To provide some protection against tuberculosis

Question 25

What monitoring is essential during tuberculosis treatment?

Answer 25

Liver function tests

Question 26

Fill in the blank: The __________ of tuberculosis refers to the ability of the bacteria to survive in a dormant state.

Answer 26

latency

Question 27

What is the significance of MDR-TB?

Answer 27

It refers to multidrug-resistant tuberculosis that is resistant to at least Isoniazid and Rifampicin.

Question 28

Which drug is used as a last resort for extensively drug-resistant tuberculosis (XDR-TB)?

Answer 28

Bedaquiline

Question 29

What is a major concern when treating tuberculosis with multiple drugs?

Answer 29

Potential drug interactions and side effects

Question 30

True or False: Tuberculosis can be cured with appropriate antibiotic therapy.

Answer 30

True

Question 31

What is the purpose of using a combination of drugs in tuberculosis treatment?

Answer 31

To prevent the development of drug resistance

Question 32

Fill in the blank: The __________ test is used to diagnose active tuberculosis.

Answer 32

tuberculin skin

Question 33

What is the role of supportive therapy in tuberculosis management?

Answer 33

To enhance overall health and support recovery.

Question 34

What is the main route of administration for tuberculosis medications?

Answer 34

Oral