Lesson 14: Disorders Of Defecation Flashcards

1
Q

Diarrhea - Acute

A
  • <14 days
  • Sudden onset with rapid resolution

Caused by
- Infectious process
- Acute exacerbation of chronic inflammatory process
- Initiation of tube feed after extended NPO status

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2
Q

Diarrhea - Chronic

A

Caused by
- Chronic motility disorder (ie. IBS)
- Chronic inflammatory disorder (ie. Crohns or UC)
- Specific food intolerances/malabsorption syndrome
- Peristalsis stimulants

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3
Q

Diarrhea - Assessment

A
  • Onset + duration of problem
  • Stool frequency, volume, consistency, color, odor
  • Prior stool patterns
  • Any associated symptoms
    — Cramping
    — Nausea
    — Vomiting
    — Incontinence
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4
Q

Acute Diarrhea - Presentation

A

S/S of systemic illness
- Fever
- Chills
- Joint point
- General malaise

S/S of dehydration
- Dry mouth
- Tenting of skin
- Concentrated urine
- Dizziness
- Lethargy
- Hypotension

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5
Q

Chronic Diarrhea - Presentation

A

Evidence of IBD
- Cramping pain
- Blood in stool
- Weight loss
- Nocturnal diarrhea
- Nausea/vomiting

Evidence of IBS
- Epigastric pain relieved by bowel movements

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6
Q

Management - Chronic Diarrhea

A

Correct etiologic factors

C.Diff
- Antibiotics
- Probiotics
- ?fecal transplant

IBD
- Anti-inflammatories
- Immunomodulators

IBS
- Education
- Counseling
- Symptom management

Malabsorption
- Dietary modifications

Ileal resection
- Bile salt binding agents

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7
Q

Management - Acute Diarrhea

A

Rehydrate if indicated

Rx
- Antibiotics if bacterial infection
- Antimotility agents
- Bismuth subsalicylate
- Probiotics

Dietary medications to thicken stool
- BRAT diet

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8
Q

Management - Diarrhea d/t fecal incontinence

A

Anorectal pouch
- Adheres to skin around anus
- Can connect to drainage bag
- Ensure skin is clean + dry
- Treat denuded areas with crusting

Bowel management system
- FlexiSeal
- Only if stool is liquid or high volume
- Contraindications
— Clotting disorders
— Rectal pathology
— Lax sphincter
- Irrigate tube routinely to avoid blockage

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9
Q

Diarrhea Management - Skin Care

A

If intact skin
- Moisture-barrier ointment with zinc oxide

If damaged skin
- Zinc oxide to damaged skin
- Crusting with ostomy powder prior to zinc application
- Hydrophilic paste (ie. Triad)

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10
Q

Constipation

A

Def: 2 or more of the following for the past 6 months
- Straining with >25% of bowel movements
- Lumpy or hard stools with >25% of bowel movements
- Sensation of incomplete evacuation with >25% of bowel movements
- Sensation of obstruction or blockage with >25% of bowel movements
- Less than 3 bowel movements per week
Infrequent loose stools unless laxative administered

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11
Q

Simple Constipation

A

Occasional difficulty with stool elimination
- Dietary issues
- Environmental factors
- Pregnancy

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12
Q

Functional Normal Transit Constipation - Pathology

A
  • Bowel works but insufficient stimulation for mass movements + defecation
  • Normal peristaltic activity in response to distension, eating, and parasympathetic stimulation
  • Caused by factors outside the bowel
    — Insufficient fiber + fluid
    — Immobility + activity
    — Medications (opioids, antacids, anticholinergics)
  • Hard, small stools cannot distend colon enough to cause mass movements
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13
Q

Functional Normal Transit Constipation - Presentation

A
  • Hard, dry stools
  • Straining with defecation
  • Use of laxatives, suppositories, enemas
  • <3 stools per week
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14
Q

Functional Normal Transit Constipation - Management

A

Colonic clean out if evidence of retained stool/impaction
- Top-down approach is best
— Osmotic laxatives
— Stimulant agents
- Bottom-up approach
— If patient lacks sensory awareness/sphincter control
— More predictable time frame for effect
— Include fleet enemas or milk+molasses enema
- Increase activity
- Eliminate constipating medications
- Assure adequate fluid + fiber intake
— 2 L water ; 25-38g fiber / day
— High fiber diet
— Bran mixtures
— Fiber supplements
— Softener + stimulant combo

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15
Q

Functional Normal Transit Constipation - Patient Education

A
  • Colon function + health
  • Importance of fiber + fluid
  • Importance of responding to urge to go
  • Correct posture
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16
Q

Slow Transit Constipation - Pathology

A

Constipation d/t bowel dysfunction

Reduced in frequency + amplitude of peristaltic waves

17
Q

Slow Transit Constipation - Etiology

A

Neurologic process disrupts autonomic pathways to bowel

Autonomic neuropathy d/t diabetes

IBS

18
Q

Slow Transit Constipation - Clinical Presentation

A
  • Very infrequent urge to defecate (1-4 times/month)
  • Very large bowel movements
  • Bloating + anorexia
  • Poor response to fiber + laxatives
19
Q

Slow Transit Constipation - Diagnostics

A
  • colonic motility study
  • video capsule endoscopy
  • motility study with wireless motility capsules
20
Q

Slow Transit Constipation - Management

A

GI referral for definitive diagnosis + management

Rx
- Stool softeners daily
- Osmotic laxatives daily with stimulant PRN
- Lubiprosone
— For management of chronic constipation
- Linaclotide
— Approved for idiopathic STC

Surgical
- Colectomy with ileorectal anastomosis
- Antegrade continence enema
- Sacral neuromodulation

21
Q

Obstructed Defecation - Pathology

A

Difficulty eliminating stool d/t outlet obstruction

Stool does not pass through anal canal normally

22
Q

Obstructed Defecation - Etiology

A

Structural defects
- Rectocele: straining causes rectum to bulge into vaginal vault
- Rectoanal intussusception: straining causes rectum to intussuscept into anal canal
- Perineal descent: pelvic floor drops of position with straining/partially occludes anus
- Rectal prolapse: rectum protrudes through anal canal and blocks anus

23
Q

Obstructed Defecation - Clinical Presentation

A
  • Difficult stool elimination that persists even when consistency is normal
  • Excessive straining + feelings of incomplete emptying
  • Use of digital maneuvers to facilitate evacuation
24
Q

Obstructed Defecation - Diagnostics

A

Defecography

25
Obstructed Defecation - Management
Rectocele - Pessary - Surgical intervention Perineal descent - Maintenance of soft + formed stool - Strengthen pelvic floor muscles Rectal prolapse - Surgical repair Rectoanal intussusception - Surgical repair Pelvic floor dyssynergia - Measures to create soft, formed stool - Biofeedback for relaxation of pelvic floor muscles
26
Irritable Bowel Syndrome - Criteria
Recurrent abdo pain/discomfort for at least 3 days/month with 2 or more of the following - Pain/discomfort improved with defecation - Onset of pain/discomfort associated with change in stool frequency - Onset of pain/discomfort associated with change in stool form/consistency
27
Irritable Bowel Syndrome - Classifications
Constipation-predominant - CP-IBS or IBS-C Diarrhea-predominant - DP-IBS or IBS-D Mixed pattern - IBS-M Pain-predominant - PP-IBS
28
Irritable Bowel Syndrome - Etiology/Pathology
- Abnormal permeability of intestinal mucosa - Alternation in bacterial balance in gut — Inflammation alters gut motility — Enteric nervous system dysfunction - Autonomic nervous system dysfunction - Alteration in immune system function - Psychological distress - Role of diet
29
Irritable Bowel Syndrome - Assessment
- Based on history + physical + symptom diary - Use of Bristol Stool Chart
30
Irritable Bowel Syndrome - Diagnostics
- Fecal occult blood to r/o cancer - Hemoglobin to r/o anemia - Erythrocyte Sedimentation Rate to r/o inflammatory process - Testing for Celiac disease Additional testing only for “red flag” symptoms - Bleeding - Anemia - Fever - Unintended weight loss - Family history of colorectal cancer - Frequent nocturnal symptom - Recent onset + progressive severity - Recent antibiotic use - Abdominal mass - Lymphadenopathy
31
Irritable Bowel Syndrome - Management
Diet - Trial reduction in fermentable carbs + lactose - Dietary intake + symptom chart to identify individual food triggers Pharmacologic - IBS-C — Fiber + fluid titration, lubiprostone - IBS-D — Loperamide, diphenoxylate, cholestyramine — Alosetron for severe cases in women —— Can cause severe ischemic colitis - PP-IBS — Hyoscyamine, amitriptyline, nortriptyline
32
Irritable Bowel Syndrome - Patient Education
- Identify + address concerns - Emphasize no malignancy/ non-life threatening - Focus is symptom management
33
Hierarchy of Laxatives
Fiber supplements - Bulk laxatives + fluids Osmotic + hypertonic agents - Saline cathartics — Milk of Magnesia — Magnesium Citrate — Fleet Enema - Lactulose agents - Sorbitol agents - Polyethylene Glycol agents — Miralax — Colyte Stimulant agents - Sennosides - Bisacodyl - Glycerin