LESSON 8 Flashcards
a membrane made of two layers of phospholipids with embedded proteins that separates the insides of the cell from its environment
cell membrane
This is a group of organic compounds that are insoluble in water.
lipids
Examples include fats, waxes, oils, and hormones.
lipids
hydrophilic head
phosphate group
hydrophobic tail
fatty acids
having both hydrophilic and hydrophobic parts.
amphipathic molecule
allows certain substances to pass through but not others.
semi- permeable
hese molecules are madeup of building blocks called amino acids joined by peptide bonds.
proteins
_______ penetrate the hydrophobic core
Integral proteins
Integral proteins that span the membrane are called __________
transmembrane proteins
The hydrophobic regions of an integral protein consist of one or more stretches of ____________, often coiled into ___________
nonpolar amino acids; alpha helices
___________ - spans across the membrane
polytropic or transmembrane
_________ attached to only one side of the membrane
monoprotic
are bound to the surface of the membrane
Peripheral proteins
Functions of Proteins
receptor
channel
transmembrane transport
adhesion
cell-cell recognition
enzymatic function
________ are a special class of proteins that function by binding a specific ligand molecule.
Receptors
When a ligand binds to its ______, the ______ can change conformation, transmitting a signal into the cell.
receptor
common ligands are the
neutral molecules water (H2O), ammonia (NH3), and carbon monoxide (CO) and the anions cyanide (CN-), chloride (Cl-), and hydroxide (OH-).
A __________ is a special arrangement of amino acids which embeds in the cell membrane, providing a hydrophilic passageway for water and small, polar ions.
channel protein
Like all transport proteins, each _________ has a size and shape which excludes all but the most specific molecules.
channel protein
A ___________ is seen, embedded within the membrane. Ions, the small green hexagons, travel through the channel protein.
generic channel protein
A _____________ is a membrane protein involved in the movement of ions, small molecules, and macromolecules, such as another protein, across a biological membrane.
membrane transport protein (or simply transporter)
Only ________ proteins can function on both sides of the bilayer or transport molecules across it
transmembrane
__________ are transmembrane proteins that bind signal molecules in the extracellular space and generate different intracellular signals on the opposite side of the plasma membrane.
Cell-surface receptors