Lewy Body Dementia

Question 1

pathological feature of LBD?

Answer 1

alpha synuclein cytoplasmic inclusions in substantia nigra, paralimbic, and neocortical areas

Question 2

features of LBD?

Answer 2

progressive cognitive impairment earlier then parkinsonism, cognition may fluctuate, early impairment in attention and executive function, visual hallucination

Question 3

diagnosis of lewy body dementia is?

Answer 3

clinical , single photon emission compute tomography (SPECT)

Question 4

management of lewy body dementia?

Answer 4

acetylcholinesterase inhibitors (donepezil, rivastigamine) and memantine

Question 5

what should be avoided in Lewy body dementia?

Answer 5

neuroleptics- may develop irreversible parkinsonism

Question 6

lewy body dementia features?

Answer 6

fluctuating progressively worsening cognition, visual hallucinations, and REM sleep disorder. She may also have parkinsonian symptoms on examination.