Limb Development Flashcards
1
Q
Skeletal pattern formation from proximal to distal
A
Humerus - Stylopod
Ulna & Radius - Zeugopod
Metacarpals & Digits - Autopod
2
Q
Tissues developed by the following germ layer origins:
Somites (Sclerotome)
Somites (Myotome)
Somites (Dermatome)
Neural crest cells
Surface ectoderm
A
- Cartilage -> Bone
- Skeletal muscle
- Dermis, connective tissues
- Neurons
- Skin epidermis and specializations
3
Q
STEPS IN TETRAPOD LIMB DEVELOPMENT
A
A. Specification
B. Determination
C. Induction (EMT)
D. Initiation
E. Outgrowth
F. Patterning
4
Q
Limb Disk -> Limb Bud
A
5
Q
Where is Hox6 - Hox9 found in an embryo
A
Thoracic region
6
Q
Where is Hox5 found in an embryo
A
Cervical region
7
Q
Where is Hox10 found in an embryo
A
Lumbar region
8
Q
Retinoic acid (RA) plays a crucial role in forelimb development, primarily by influencing the initiation of limb bud formation
A
9
Q
A
