Lipid Transport Flashcards

1
Q

At which position on the cholesterol molecule below does acyl cholesterol acyl transferase (ACAT) carry out its reaction?

A

D.
acyl cholesterol acyl transferase (ACAT) is the enyzme that converts cholesterol into cholesterol esters

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2
Q

Which apolipoprotein is characteristic of chylmicrons?

A

ApoB48

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3
Q

Which one of the following classes of lipids is not associated with chylomicrons?
A. Cholesterol
B. Cholesterol esters
C. Free fatty acids
D. Phospholipids
E. Triglycerides

A

C. Free fatty acids

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4
Q

Which one of the following contains the least quantity triglycerides?
A. chylomicrons
B. HDL
C. IDL
D. LDL
E. VLDL

A

B. HDL

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5
Q

Which lipoprotein floats in water?
A. Chylomicrons
B. High desnity lipoprotein
C. Intermediate density lipoprotein
D. Lipoprotein (a)
E. Low density lipoprotein

A

A. Chylomicrons

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6
Q

For decades, specific laboratory techniques have been used to differentiate and quantify the various lipoproteins. What are the two primary properties of lipoproteins these techniques are measuring?

A
  • Electrophoretic mobility
  • ultracentrifugal density
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7
Q

The surface of a lipoprotein is…

A

a monolayer of phospholipids, cholesterol, and apolipoproteins

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8
Q

Which lipoprotein does not contain apolipoprotein B?
A. Chylomicron remnants
B. High density lipoprotein
C. Intermediate density lipoprotein
D. Low density lipoprotein
E. Very low density lipoprotein

A

B. High density lipoprotein

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9
Q

Which one of hte following lipids is found in the core of a lipoprotein molecule?
A. Cholesterol
B. Cholesteryl ester
C. Deoxycholic acid (a bile acid)
D. Phosphatidylcholine
E. Oleic acid

A

B. Cholesteryl ester

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10
Q

Which of the following has the least amount of triglycerides?
A. Chylomicrons
B. HDL
C. IDL
D. LDL
E. VLDL

A

B. HDL

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11
Q

True or False?

Chylomicrons are the largest and least dense of the lipoproteins.

A

True

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12
Q

True or False?

HDL appears to be anti-atherogenic.

A

True

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13
Q

True or False?

High density lipoproteins (HDL) are involved in the transport of cholesterol from the periphery to the liver.

A

True

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14
Q

True or False?

The major prtein moieties of HDL are apolipoproteins A-I and A-II

A

True

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15
Q

Fatty acid is transported from adipose tissue to energy-utilizing tissues as what molecule?

A

Free fatty acids bound to albumin

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16
Q

The exchangeable apolipoproteins are functional components in lipoprotein metabolism and carry out many functions. Whch apolipoprotein is involved in lipoprotein lipase (LPL) activation in triglyceride hydrolysis?

A

ApoCII

17
Q

What is the role of lipoprotein lipase?

A

hydrolyze triglycerides in plasma lipoproteins