Lipids (Apolipoproteins)

Question 1

Protein portion of lipoprotein

Answer 1

Apolipoprotein

Question 2

Apo A-I is found in

Answer 2

HDL

Question 3

Activates lecithin-cholesterol acyltransferase (LCAT)

Answer 3

Apolipoprotein A-I

Question 4

Synthesized jn the liver and intestines

Answer 4

Apo A-I

Question 5

Apo A-II is found in

Answer 5

HDL

Question 6

Inhibits lipoproteins and hepatic lipases
Increases plasma triglyceride

Answer 6

Apo A-II

Question 7

Apo A-IV is found in

Answer 7

HDL
CM
free in plasma

Question 8

Cofactor for lecithin-cholesterol acyltransferase
Increases during fat absorption
HDL synthesis

Answer 8

Apo A-IV

Question 9

Apo B-100 is found in

Answer 9

VLDL
LDL

Question 10

Very large structural protein
Synthesized in liver with endogenous lipids

Answer 10

Apo B-100

Question 11

Apo B-48 is seen in

Answer 11

CM

Question 12

Synthesized in the intestines ONLY

Answer 12

Apo B-48

Question 13

Apo C-I is found in

Answer 13

CM
VLDL

Question 14

Inhibits hepatic uptake of VLDL and cholesterol ester transfer protein

Answer 14

Apo C-I

Question 15

Apo C-II is found in

Answer 15

CM
VLDL

Question 16

activates lipoprotein lipase
deficiency causes reduced clearance of triglyceride-rich lipoproteins

Answer 16

Apo C-II

Question 17

Apo C-III is found in

Answer 17

VLDL
HDL

Question 18

Inhibits lipolysis and reduces clearance of triglyceride-rich lipoprotein

Answer 18

Apo C-III

Question 19

Apo D is found in

Answer 19

HDL

Question 20

Activates lecithin-cholesterol acyltransferase

Answer 20

Apo D and Apo A-I

Question 21

Esterifies cholesterol in plasma

Answer 21

Lecithin-cholesterol acyltransferase

Question 22

Apo E is found in

Answer 22

CM
HDL
IDL intermediate density lipoprotein
HDL
Remnants

Question 23

Targets CM and VLDL remnants to hepatic receptor
Binds to cell surface LDL receptors and proteoglycans

Answer 23

Apo E

Question 24

What subtypes of Apo E are associated with higher risk of coronary heart disease and alzheimer’s disease

Answer 24

E-2
E-3
E-4

Question 25

What apolipoprotein is associated with type 3 hyperlipoproteinemia

Answer 25

E-2

Question 26

Apo F is found in

Answer 26

HDL LDL VLDL

Question 27

Apo H is found in

Answer 27

VLDL

Question 28

Apo J is found in

Answer 28

None

Question 29

Apo L is found in

Answer 29

HDL

Question 30

Apo M is found in

Answer 30

HDL CM LDL VLDL

Question 31

Apo (a) is found in

Answer 31

Lipoprotein (a)

Question 32

Regulates Cholesteryl ester transfer protein function

Answer 32

Apo F

Question 33

Related to activation of lipoprotein lipase Triglyceride metabolism

Answer 33

Apo H

Question 34

Involved in apoptosis Known as clusterin Linked to neurologic diseases like Pick's and Alzheimer's

Answer 34

Apo J

Question 35

May be linked to reverse cholesterol transport

Answer 35

Apo L

Question 36

Linked to HDL remodeling

Answer 36

Apo M

Question 37

Bound to apo B-100

Answer 37

Apo (a)