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PIPH FINALS > LIQUID DOSAGE FORMS > Flashcards

LIQUID DOSAGE FORMS Flashcards

1
Q

Are liquid preparations that contain one or more chemical substances dissolve in a suitable solvent or mixture of mutually miscible solvents

A

Solutions

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2
Q

What are the advantages of solutions

A

Completely homogeneous doses
Immediate availability for absorption and distribution
Provides a flexible dosage form through easy to swallow, can be used by any route of administration and easy to adjust dose

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3
Q

A represent by true or colloidal solution

A

Monophasic liquid dosage forms

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4
Q

Solutions containing high concentration of sucrose or other sugars

A

Syrups

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5
Q

Examples of syrups

A

Cherry syrup
Cocoa syrup
Orange syrup
Raspberry syrup

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6
Q

Nearly saturated aqueous solution of sucrose 85% weight per volume

A

Syrup according to national formulary or simple syrup

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7
Q

Inherently stable and resistant to the growth of microorganisms when properly prepared and maintained

A

Simple syrup

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8
Q

Methods of preparation for syrups

A

Percolation
Reconstitution
Addition of sucrose to medicated or flavored liquid
Solution by agitation without the aid of heat
Solution by agitation with the aid of heat

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9
Q

Give the importance of syrups

A

It retards oxidation because it’s partly hydrolyzed into the reducing sugar
It prevents the composition of many vegetable substance because it’s have high osmotic pressure which prevent the growth of bacteria
They are palatable due sweet taste

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10
Q

Are clear pleasantly flavored sweetened hydro alcoholic solutions intended for oral use

A

Elixirs

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11
Q

Alcohol content of elixir

A

5 to 40%

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12
Q

Alcohol content of aromatic elixir

A

22%

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13
Q

Methods of preparation of elixirs

A

Solution with agitation
Admixture of two or more liquid ingredients

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14
Q

Are alcoholic or hydro-alcoholic solutions of volatile substances

A

Spirits or essences

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15
Q

Alcohol content of spirits or essences

Use of spirits or essences

A

60%

Flavoring agents and vehicle

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16
Q

Spirits or essences and aromatic waters are stored in

A

Tight and light resistant containers

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17
Q

Are alcoholic or hydro alcoholic solutions prepared from vegetable materials or from chemical substances

A

Tinctures

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18
Q

Alcohol content of tincture

A

15 to 80%

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19
Q

What is the preparation of tinctures

A

Maceration and percolation

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20
Q

Examples of tinctures

A

Iodine Tincture
Opium tincture

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21
Q

Are liquid preparations of vegetable drugs containing alcohol as solvent preservative or both and so me that unless otherwise specified in an individual monograph

A

Fluid extract

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22
Q

H ml of fluid extract contains how many standard drug

A

1 g

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23
Q

Preparation of fluid extracts includes

A

Process A
Process B and D
Process E

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24
Q

Are clear aqueous solution saturated with volatile oils or other aromatic or volatile substances

A

Aromatic Waters

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25
Q

Aromatic waters are also called as

A

Medicated waters

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26
Q

Aqueous phasein some emulsions or suspensions

A

Aromatic Waters

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27
Q

Methods of preparation of aromatic waters

A

Solution of the aromatic substances with or without use of dispersing agent
Distillation

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28
Q

Are aqueous solutions used for treating The parents and not so pharynx by forcing air from the lungs

A

Gargles

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29
Q

Are aqueous solution use for its deodorant refreshing or antiseptic effect or for control of plaque

A

Mouth washes

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30
Q

Intended for tropical application to the skin or mucous membranes

A

Topical solutions

31
Q

Are aqueous or oliganous solutions in the form of course droplets are finally divided solids to be applied topically it is most usually to the nasopharyngeal tract or to the skin

A

Sprays

32
Q

Locally applied solutions to the constrict force and precipitate proteins

A

Astringent

33
Q

Examples of astringent

A

Aluminum acetate
Aluminum sub acetate
Calcium hydroxide

34
Q

Kill microorganisms when applied to the skin or mucous membranes

A

Topical anti-infective

35
Q

Examples of topical anti-infective

A

Povidone iodine
Thimerosal
Hydrogen peroxide

36
Q

Rectal solutions employed to evacuate the bowel and influence the general system of absorption or to affect locally the site of disease

A

Enemas

37
Q

Are aqueous solutions directed against a part or into a cavity of the body functions as a cleansing or antiseptic agent and are frequently dispensed in the form of a powder with the directions for dissolving in a specified quantity of warm water

A

Douches

38
Q

Are not aqueous alcoholic or oligano solutions or emulsions of various medicinal substances intended to be rubbed on the skin

A

Liniments

39
Q

Liniments are also called as

A

Embrocations

40
Q

Are liquid preparations composed of pyroxylene dissolved in an aqueous solvent mixture usually composed of alcohol and ether with or without added medicinal substances

A

Collodions

41
Q

Pyroxylin is also called

A

Soluble gun cotton

42
Q

Paroxetine is produced through the action of what

A

Nitric acid and sulfuric acid
3:1
Purified cotton

43
Q

Flexible colloidon is prepared by the addition of what

A

3% castor oil for flexibility
2% camphor for waterproofing

44
Q

Are aqueous solutions designed to be administered to the nasal passages in drops or sprays may contain preservatives buffer antioxidant and surfactan vehicle use is usually water but co solvent system may be used

A

Nasal solution

45
Q

Are intended for installation into the ear

A

Otic solution

46
Q

What is the vehicle of otic solution

A

Glycerin or water or co solvent

47
Q

Are sterile pyrogen-free and particle free solution suitably compounded and package for installation into the eye

A

Ophthalmic solution

48
Q

Optimic solutions - PH and positive PH

A

7.4
6.5 to 8.5

49
Q

Status solutions used to wash or bath surgical incisions wounds or body tissues

A

Irrigating solution

50
Q

Injected through the skin or directly into the blood vessel muscle organ or tissue

A

Parental solutions

51
Q

Must conforms with strict requirements for microbiological impurity particulate matter and pyrogenicity

A

Parenteral solutions

52
Q

Routes of administration of parenteral solutions

A

Intradermal or intracutenous
Subcutaneous
Intramuscular
Intravenous
Intra arterial
Intra thecal
Intra spinal
Epidural

53
Q

The liquid which consist of two phases are known as

A

BIPHASIC liquid dosage forms

54
Q

Is a bifasic liquid dosage forms containing two immiscible liquid

A

Emulsion

55
Q

Two immiscible liquids under emulsion

A

Continuous phase and dispersed phase

56
Q

Types of emulsion

A

Oil in water
Water in oil
Multiple emulsions
Micro emulsions

57
Q

Liquid dosage forms containing finely divided drug particles distributed somewhat uniformly throughout a vehicle in which the drug exhibits a minimum degree of solubility

A

Suspensions

58
Q

Purposes for formulating a suspension

A

Sustaining effect
Stability
Taste

59
Q

is a thermodynamically unstable system
consisting of at least two immiscible liquid phases one of
which is dispersed as globules in the other liquid phase
stabilized by a third substance

A

Emulsion

60
Q

Emulsion is a thermodynamically unstable system
consisting of at least two immiscible liquid phases one of
which is dispersed as globules in the other liquid phase
stabilized by a third substance called

A

Emulsifying agent

61
Q

The globule size in emulsion varies from

A

0.25-25 nanometer

62
Q

are semisolid systems consisting of dispersions of small or
large molecules in an aqueous liquid vehicle rendered jelly-like
by the addition of a gelling-agent

A

Gels

63
Q

sometimes used for suspension in aqueous
vehicles intended for oral

A

Milk

64
Q

often used to describe
suspensions of inorganic acids such as clay in
water

A

Magma

65
Q

generally suspensions of
solid materials in an aqueous vehicle.

A

Lotion

66
Q

are semisolid preparations intended for external application
to the skin or mucous membranes

A

Ointments

67
Q

make the skin more pliable

A

Emollients

68
Q

Are semisolid preparation containing one or
more medicinal agents dissolved or
dispersed in either a W/O emulsion or an
O/W emulsion or in another type of waterwashable bases.

A

Creams

69
Q

oil-in-water emulsion containing large
percentage of water and stearic acid or
other oleaginous component

A

Vanishing cream

70
Q

are semisolid preparations intended for application to the
skin, and generally contain a larger proportion of solid
material than ointments and therefore are stiffer

A

Pastes

71
Q

are plastic masses containing gelatin (15%),
glycerin (40%), water (35%) and an added
medicinal substance (10%) such as zinc oxide

A

Glycerogelatins

72
Q

Are solid dosage forms intended for insertion into
body orifices where they melt, soften, or
dissolve and exert local or systemic effects.
•
useful in infants, debilitated or comatose patients,
patients who vomit, who have nausea or
gastrointestinal disturbances

A

Suppositories

73
Q

FOR VARICOSE ULCER– re
wounds that are thought to occur due to improper
functioning of venous valves, usually of the legs

A

Zin gelatin boot

PIPH FINALS (5 decks)

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