Lithium Flashcards
1
Q
MOA Lithium
A
unknown
alters neuronal sodium transporter and influences reuptake of serotonin and NE
2
Q
indications for lithium
A
Bipolar disorder
Acute mania
Schizoaffective disorder
3
Q
Lithium and suicide risk
A
Lithium decreases suicide risk
4
Q
Common endocrine ADE of lithium
A
hyperparathyroidism
hypothyroidism
hypermagnesemia
hypercalcemia
nephrogenic DI —-> hyponatremia
5
Q
Contraindications for lithium
A
pregnancy - ebstein anomaly if taken during first trimester
severe renal disease (KIDNEY)
cardiac disease
6
Q
Drug interactions with lithium
A
Blood level is increased by:
Dehydration
Thiazides
Tetracyclines
NSAIDs
7
Q
Neuro ADEs of lithium
A
seizures
tremor
HA
sedation
8
Q
GI ADE of lithium
A
N/V
Diarrhea
weight gain
9
Q
Cardiac ADE of lithium
A
edema
arrythmias
ECG changes
10
Q
hematological ADE lithium
A
leukocytosis
