Liver Disease Pathophysiology Flashcards

1
Q

What are the functions of the liver?

A
  1. metabolism
  2. detoxification
  3. protein synthesis
  4. synthesis of clotting factors
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2
Q

How does the liver metabolize carbohydrates?

A

glycogenosis
glycogenolysis
gluconeogenesis

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3
Q

How does the liver metabolize fat?

A

lipoprotein synthesis
cholesterol synthesis

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4
Q

How does the liver metabolize protein?

A

conversion of ammonia into urea as part of protein degradation

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5
Q

How does the liver detoxify drugs and other substances?

A

oxidation and conjugation

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6
Q

What protein is synthesized by the liver?

A
  1. albumin
  2. cholesterol
  3. glycoprotein
  4. haptoglobin
  5. clotting facotrs
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7
Q

What procoagulants are produced by the liver?

A
  1. prothrombin
  2. Factors V, VIII, IX, X, XI
  3. fibrinogen
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8
Q

What anti-coagulants are produced like the liver?

A
  1. Protein C
  2. Protein S
  3. Anti-thrombin
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