Liver medications Flashcards
(31 cards)
What is the most common cause of acute liver failure in the UK?
Paracetamol overdose
What is used to grade the extent of hepatic encephalopathy?
West haven criteria
How is hepatic encephalopathy treated?
Lactulose
How are ascites treated?
Spironolactone
What is used to assess prognosis and treatment required for chronic liver failure?
Child pugh score
What are the stages of alcoholic liver disease?
Steatosis –> alcoholic hepatitis –> alcoholic cirrhosis
What is seen on biopsy of those with alcoholic liver cirrhosis?
Mallory cytoplasmic inclusion bodies
How is delirium tremens treated?
Chlordizepoxide
What are the stages of fatty liver disease?
Hepatosteatosis –> non alcoholic steatohepatitis –> fibrosis –> cirrhosis
What does HBcAb represent?
Exposure to HBV at some point
What does HBcIgM/G represent?
- HBcIgM = acute infection
- HBcIgG = chronic infection
Who is affected by type 1 vs 2 autoimmune hepatitis?
- 1 = adult females
- 2 = young females
What antibodies are associated with type 1 vs 2 autoimmune hepatitis?
- 1 = ANA and ASMA
- 2 = ALC-1 and ALKM-1
What is a blood marker for pancreatic cancer (and lots of other cancers)?
Ca19-9
Who is affected most by PBC?
Females (40-50)
Who is affected most by PSC?
Males (40-50)
What is the serology of PBC vs PSC?
- PBC = AMA
- PSC = pANCA
How is PBC vs PSC imaged?
- PBC = USS
- PSC = MRCP
How is PBC vs PSC managed?
- PBC = Ursedeoxycholic acid
- PSC = conservative
How is pruritus treated?
Cholestyramine
What blood marker is more specific and sensitive to pancreatitis?
Lipase = more specific and sensitive
What is a complication of pancreatitis?
Systemic inflammatory responce syndrome
What medication can be given to stop oesophageal varices bleeding?
IV terlipressin
What chromosome is affected in haemochromatosis?
Chromosome 6
