LONG TEST 1 Flashcards
(30 cards)
Pulmonary reactions that include hypersensitivity pneumonitis, which is characterized by “farmer’s lung” is under what type of hypersensitivity reaction?
a. Type I hypersensitivity
b. Type II hypersensitivity
c. Type Ill hypersensitivity
d. Type IV hypersensitivity
Type Ill hypersensitivity
What test procedure should be performed when testing for antibodies to a specific allergen?
a. RIST
b. RAST
c. CRP
d. RPR
RAST
What method works on the principle of complement fixation test?
a. Kahn test
b. Laurell technique
c. VDRL
d. Wasserman
Wasserman
In the Enzyme - linked immunosorbent assay (ELISA), the visible reaction is due to a reaction between:
a. Enzyme and antibody
b. Enzyme and substrate
c. Fluorescent dye and Antigen
d. Latex particles and antibody
Enzyme and substrate
What is the indicator system used in the complement fixation test?
a. Sensitized sheep red blood cells
b. Fluorescent - labelled antihuman globulin
c. Enzyme labelled antihuman globulin
d. Guinea pig kidney cells
Sensitized sheep red blood cells
In patients with human immunodeficiency virus infection, immune status can be monitored by measuring the ratio of _
a.CD2+ cells to CD4+ cells
b. CD4+ cells to CD8+ cells
c. Lymphocyte to monocybes
d. T cells to B cells
CD4+ cells to CD8+ cells
Which of the following is a confirmatory test for HIV?
a. Westernblot
b. PCR
c. Both
d. Neither
e. Both
Westernblot
Which of the following is most likely a Positive in the Western blot test for infection with HIV?
a. Band at p24
b. Band at gp60
c. Bands at p24 and p 31
d. Bands at p24 and gp120
Bands at p24 and gp120
Which CD4 : CD8 ratio is most likely in a patient with Acquired Immunodeficiency Syndrome (AIDS)?
a. 2: 1
b. 3: 1
c. 2: 3
d. 1: 2
1: 2
Which of the following Is used as the most sensitive indicator of the effectiveness of antiretroviral treatment for
monitoring an HIV?
a. HIV antibody titer
b. CD4 : CD8 ratio
c. HIV viral load
d. Absolute total T-cell count
HIV viral load
Which of the following test is the most suitable for testing HIV vertical transmission in a newborn?
a. HIV PCR test
b. CD4 count
c. Rapid HIV Antibody test
d. HIV IgM antibody test
HIV PCR test
What is the best method for screening cerebrospinal fluid for syphilis?
a. Darkfield microscopy
b. FTA-abs
c. RPR
d. VRDL
VRDL
The rapid plasma reagin (RPR) test is rotated at what speed and length of time?
a. 100 rpms for 8 minutes
c. 120 rpms for 8 minutes
b. 100 rpms for 10 minuets
d. 120 rpms for 20 minutes
100 rpms for 8 minutes
The Treponema pallidum Immobilization (TPI) test requires
a. Fixed Treponema pallidum on the glass slide
b. Live Treporema pallidum
c. Reagin antibody
d. Treponema pallidum extract
Live Treporema pallidum
Cytomegalovirus belongs to what group?
a. Adenovirus
b. Retrovirus
c. Herpes virus
d. Picornavirus
Herpes virus
Which of the following virus/es should be tested prior to Blood transfusion?
a. CMV
b. EBV
c. HTLV-ITI
d. HDV
CMV
What is the diagnostic method used to confirm equivocal CMV IgM results?
a. ELISA
b. PCR
c. Chemiluminiscence
d. IFA
ELISA
What is the rapid test used for diagnosis of CMV in immunocompromised patients or organ donors?
a. ELISA
b. PCR
c. Chemiluminiscence
d. IFA
PCR
Transfusion-acquired CMV infection can manifest which of the following?
a. Mononucleosis-like syndrome
c. Hepatitis
b. Rejection of transplanted organ
d. All of the above
All of the above
What type of cell culture best supports the growth of cytomegalovirus?
a. HeLa cells
b. Hep-2 cells
c. Human fibroblast cells
d. Primary monkey kidney cells
Human fibroblast cells
The heterophil antibody produced in infectious mononucleosis is classified as what type of immunoglobulin?
a. IgA
b. IgD
c. IgG
d. IgM
IgM
Which of the following is NOT a characteristic of heterophil antibodies produced in infectious mononucleosis?
a. Absorbed by guinea pig kidney cells
c. Absorbed by beef red cells
b. Not absorbed by guinea pig kidney cells
d. React with horse, ox and sheep red cells
Absorbed by guinea pig kidney cells
Which statement is TRUE about non-Forssman heterophile antibody?
a. It is not absorbed by guinea pig antigen
b. It is absorbed by guinea pig antinen.
c. It does not agglutinate horse RBCS
d. It does not agalutinate sheep RBCs
It is not absorbed by guinea pig antigen
Which of the following methods is LEAST likely to give a definitive result for the diagnosis of Rheumatoid arthritis?
a. Nephelometric assay of anti-IgG
b. Anti-CCP
c. Agglutination test for Rheumatoid Factor
d. Immunofluorescence testing for antinuclear antibodies
Immunofluorescence testing for antinuclear antibodies