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Pharmacology Exam #3 > LRTS > Flashcards

Flashcards in LRTS Deck (30)
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1

What is a common organism infection in tracheitis?

S. aureus

2

What is a common organism infection in chronic bronchitis

M. catarrhalis
S. pneumonaiae
H. Influenza

3

Define Bronchitis

inflammation of walls of bronchi and bronchioles causing narrowing

4

Define Bronchiectasis

Widening of the bronchi and bronchioles
Excessive mucous production that narrows the bronchial tree

5

Who does acute bronchitis occur in?

All ages

6

Who does chronic bronchitis occur in?

Adults

7

Who does bronchiolitis occur in?

Infants

8

What is the most common microbial cause for acute bronchiolitis?

Respiratory syncytial virus (RSV)

9

Who would we consider Ribavirin treatment in for acute bronchiolitis?

Patients with:
1. Bronchopulmonary dysplasia
2. Congenital heart dz
3. Premature
4. Immunodeficiency

10

Who would we consider prophylaxis against RSV in?

Patients with underlying pulmonary or CV disease

11

Prophylaxis treatment

1. RSV immune globulin
2. Palivizumab-Preferred

12

How do we administer Palivizumab?

IM or IV infusion monthly

13

Palivizumab ADEs

1. Fever
2. Rash
3. Antibody formation
4. Rare anaphylaxis
5. Thrombocytopenia

14

What are the most common causes of acute bronchitis?

LRI pathogens:
1. Influenza virus
2. Adenovirus

15

What pathogens do we see in children?

Adults viruses + Parainfluenza virus

16

What is a frequent bacterial cause of acute bronchitis?

Mycoplasma pneumoniae-"Walking pneumonia"

17

Abx treatment for acute bronchitis

1. Azithromycin
2. Respiratory Fluoroquinolone

18

What is the hallmark definition of chronic bronchitis?

1. Cough for 3 mos. for 2. years
2. Excessive sputum production
3. Expectoration w/ persistent presence of microorganisms in pt's sputum

19

Chronic bronchitis treatment

1. Mobilize and enhance sputum expectoration-Chest physiotherapy, humidification of inspired air
2. Oxygen
3. Aerosolized bronchodilator- Albuterol
4. Abx if warranted

20

What are the most common bacterial pathogens in sputum in chronic bronchitis?

1. H. ifluenza
2. M. catarrhalis
3. S. pneumoniae

21

Abx treatment for chronic bronchitis

1. Doxycycline
2. Amoxicillin
3. TMP/SMZ

22

What is the MC pathogen causing CAP?

S. pneumoniae

23

What organism is only seen in <1 month?

Listeria

24

List first generation cephalosporin and clinical use

Cephalexin
Skin, soft tissue, UTI

25

List second generation cephalosporin and clinical use

Cefotetan, Cefoxtin
More active vs. S.pneumoniae, H.influenza

26

List third generation cephalosporin and clinical use

Ceftriaxone, Cefixime
Crosses intro CNS:
-Pneumonia
-Meiningitis
-Gonorrhea
-Beta-lactamase stable

27

List fourth generation cephalosporin and clinical use

Cefipime
Pseudomonas coverage

28

List fifth generation cephalosporin and clinical use

Ceftaroline
CAP, skin

29

Carbapenems (Beta-Lactam) SE's

CNS effects:
-Confusion
-Seizures

30

Carbapenems (Beta-Lactam) coverage

-Broad spectrum
-Grame (-) rods
-Pseudomonas