1
Q

the RT lung has how many lobes?

A

3 lobes

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2
Q

the LT lung has how many lobes?

A

2 lobes

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3
Q

why is there a difference in the number of lobes for RT and LT lungs?

A

the LT lung has less lobes (2) than the RT (3) since the heart is on the left side as well

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4
Q

which lung is wider and shorter than the other?

A

the RT lung is wider and shorter than the LT

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5
Q

Our lung is lined by two membranes called the _____

A

pleura

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6
Q

Name the two “pluera” and say which lines the SURAFCE of the lung

and which lines the THOARCIC WALL

A

SURFACE OF LUNG is lined by “Visceral pleura”

THORACIC WALL is lined by “Parietal pleura”

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7
Q

what is the space between the pleura called?

A

pleural cavity

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8
Q

The _______ is the bifurcation of the trachea

A

carina

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9
Q

where does the trachea bifurcate?

A

at the carina

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10
Q

define “bifurcate”

A

divide into two; divide into two branches

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11
Q

at what spinal column(s) is the carina roughly located?

A

T4 and T5

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12
Q

The trachea divides into the 1.______ bronchi, then into the 2.______ bronchi, then to the 3._____ bronchi, THEN to the _____, and lastly to the ______ ducts

A
  1. primary bronchi
  2. secondary bronchi
  3. tertiary bronchi
  4. bronchioles
  5. alveolar
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13
Q

what structure divides into the primary bronchi?

A

the trachea

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14
Q

what is the function of our “Alveolar ducts”

A

where oxygen and carbon dioxide are exchanged! (respiration)

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15
Q

The _____ is where blood vessels, lymphatic vessels, and nerves gain entry into the lungs

A

hilum

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16
Q

what is the main symptom of lung cacner?

A

cough

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17
Q

A Pancoast tumor occurs when ______________

A

the tumor is in the apex of the lung

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18
Q

a patient with a Pancoast tumor can experience pain where (2 specific areas), muscle _____, and ____ syndrome

A

pain under shoulder and arm

muscle atrophy

Horner syndrome

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19
Q

what is “Horner syndrome”?

A

an interruption of nerve supply from the brain

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20
Q

define “apex” (anatomically)

A

tip; top of something; forming point/top

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21
Q

what occurs when the tumor compresses the superior vena cava, which makes it difficult for the patient to breathe?

hint - ‘…syndrome…’

A

superior vena cava syndrome (SVC)

-which is considered an emergent treatment (ie. oncologic emergency)

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22
Q

what is the main method of regional spread for lung cancer?

A

Nodal involvement/lymphatic spread

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23
Q

All lymph involved with the lungs drains into the __________ nodes

A

intrapulmonary

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24
Q

lymph nodes near the Lung include (4)

A

Bronchopulmonary nodes, hilar nodes, interlobar nodes, and mediastinal nodes

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25
name the 4 superior mediastinal nodes - *hint - * PT.PRE.RT.AN SMN = SNL skit "parakeet preteen is retro az fuck"
Paratracheal Pretracheal Retrotracheal Azygos nodes
26
name the 3 Inferior Mediastinal Nodes - *hint - * SC.PE.PL
Subcarinal Paraesophageal Pulmonary ligament nodes
27
what are the three main Lung cancers?
1. Small Cell Lung Cancer (SCLC) 2. Non-Small Cell Lung Cancer (NSCLC) 3. Mesothelioma
28
SCLC can also be called “________” and includes anaplastic carcinomas
oat cell
29
T/F: SCLC includes anaplastic carcinomas
TRUE
30
describe "anaplastic"
Anaplastic is a word pathologists use to describe very abnormal-looking cancer cells. While most cancer cells share some features (shape or size) with normal cells, anaplastic cells do not look anything like normal cells.
31
the following are characteristic of SCLC or NSCLC? 1. Very aggressive 2. Metastasizes early to brain, therefore PCI (prophylactic cranial irradiation) is often used 3. Connected to tobacco use 4. Located centrally (which has worse prognosis), near proximal bronchi 5. More common in men
Small Cell Lung Cancer
32
SCLC metastasizes early to where?
brain
33
what treatment technique is often used for SCLC in regard to it metastasizing early to brain
PCI (Prophylactic Cranial Irradiation)
34
if the tumor is located centrally... does that carry a better or worse prognosis?
worse
35
which Lung cancer is typically centrally located, near the bronchi of the lung?
SCLC
36
SCLC is connected to _________ use
tobacco use
37
which lung cancer is more common in women? Which is more common in men?
SCLC is more in men NSCLC is more in women
38
which lung cancer is very aggressive and has a high mortality rate?
SCLC
39
what falls under the umbrella of NSCLC? (3 pathologies)
adenocarcinoma, large cell carcinoma, and epidermoid/squamous cell carcinoma
40
T/F: Adenocarcinomas ARE connected to tobacco use
FALSE Adenocarcinomas ARE NOT connected to tobacco use
41
which lung cancer is located more peripherally (sides) of the lungs?
NSCLC
42
which cancer of the Lung has a better prognosis? SCLC or NSCLC
NSCLC
43
which Lung cancer occurs in the linings of the Lungs? (ie. 'cancer of the pleura')
Mesothelioma
44
which Lung cancer is connected to asbestos exposure?
Mesothelioma
45
compared to NSCLC and SCLC, is Mesothelioma more common, or less?
LESS
46
DISTANT spread of Lung cancer occurs through the _________ system
circulatory
47
Lung cancer can spread to distant sites such as - (8)
liver, brain, bones, bone marrow, adrenal glands, kidneys, cervical lymph nodes, and the contralateral lung
48
what sit atop EACH kidney (so we have 2)
Adrenal glands
49
the following are characteristic of SCLC or NSCLC? 1. Located more toward the periphery (sides) of the lungs 2. More common in women 3. Better prognosis than SCLC
Non-Small Cell Lung Cancer
50
WORLDWIDE, what cancer is the most common form of cancer?
Lung cancer
51
in the US, what is the second most common cancer in both men and women?
Lung cancer
52
what cancer is the leading cause of DEATH in the US among men and women?
Lung cancer
53
the risk of developing lung cancer, like many other cancers, increases with ____
age
54
the leading risk factor for lung cancer, other than age, is what?
smoking
55
Approximately, ___% of lung cancer cases can be attributed to smoking
80
56
T/F: Individuals with a history of lung cancer are at a higher risk of developing a second lung cancer
TRUE
57
is there a difference in risk for people who smoke normal cigarettes vs people who smoke filtered cigarettes (ex. e-cigs)
No - same risk, both bad
58
Cigar Smoking and Pipe Smoking are risk factors for lung cancer... however these activities are more associated with upper aerodigestive tract OR straight up lung?
more associated with upper aerodigestive tract
59
______ is the second leading cause of lung cancer and the leading cause among non-smokers
Radon
60
exposure to ___________ is linked to mesothelioma
asbestos (mold)
61
what is the leading cause of lung cancer for non-smokers
Radon --> "Radon, air pollution, and asbestos are additional risk factors for lung cancer... considered environmental or occupational exposures"
62
define "synergistic effect"
working together
63
the ______ system transports oxygen from the air into the blood and removes carbon dioxide from the blood
respiratory system
64
blood supply to the lungs comes from the ____________ and _________ arteries
pulmonary and bronchial arteries
65
involvement of the lymphatics tends to follow the branches of the _______ tree
bronchial
66
define "hemoptysis"
blood in the sputum
67
define "dyspnea"
shortness of breath
68
what syndrome may be indicated by swelling in the face and arms, distended veins in the upper chest, dyspnea, and orthopnea?
SVC (superior vena cava syndrome)
69
define "orthopnea"
shortness of breath that occurs when lying flat
70
what is "paraneoplastic syndrome" ?
this syndrome occurs when hormone-like substances are released into the blood and cause issues in areas away from the site of cancer
71
define "atelectasis"
complete or partial collapse of a lung
72
define "pneumonitis"
inflammation of the lung
73
what happens in surgical procedure - Lobectomy
entire lung lobe is removed
74
what is the preferred surgical procedure for a patient with an early-stage Lung cancer (like stage 1 or 2)
a Lobectomy
75
what happens in surgical procedure - Pneumonectomy
An entire lung is removed
76
what is the most effective chemo agent for treating Lung cancer?
CISPLATIN
77
what is the standard of care for Lung cancer in a patient who is not a surgical candidate?
concurrent or sequential chemo and radiation with radiation doses of 45-60 Gy using standard fractionation
78
what aspect of our lungs can have dramatic effect on radiation therapy simulation and treatment planning?
lung motion
79
what is the simplest method to reduce lung motion?
breath hold
80
define "odynophagia"
painful swallowing
81
in treating lung cancer, stereotactic body radiation therapy is reserved for: A. patients with small tumors B. Medically inoperable patients with early-stage NSCLC C. Patients with SVC syndrome D. Both A and B
D. Both A and B