Lung Cance: non-small cell

Question 1

most common type of lung cancer in non smokers ?

Answer 1

adenocarcinoma

Question 2

usually in adenocarcinoma bronchoscopy does not reveal anything why ?

Answer 2

because it typically occurs peripherally

Question 3

C

Answer 3

V

Question 4

C

Answer 4

C

Question 5

C

Answer 5

V

Question 6

V

Answer 6

V

Question 7

V

Answer 7

V

Question 8

G

Answer 8

V

Question 9

C

Answer 9

V

Question 10

In non-small cell carcinoma, mediastinoscopy is always performed before surgery why ?

Answer 10

CT does not always show mediastinal lymph node involvement

Question 11

In non small cell carcinoma only 20% suitable for surgery, Surgery contraindications?

Answer 11

general health

stage IIIb or IV (i.e. metastases present)

FEV1 < 1.5 litres is considered a general cut-off point

malignant pleural effusion

tumour near hilum

vocal cord paralysis

SVC obstruction

Question 12

In non small cell carcinoma if FEV1 < 1.5 what do we do ?

Answer 12

lobectomy

Question 13

In non small cell carcinoma if FEV1 < 2 what do we do ?

Answer 13

pneumonectomy

Question 14

non small cell carcinoma has poor response to

Answer 14

chemotherapy

Question 15

X

Question 16

C

Question 17

X

Question 18

Paraneoplastic features of lung cancer
squamous cell lung cancer

Answer 18

PTH related peptide - hypercalcemia

ectopic TSH - hyperthyroidism

Question 19

in squamous cell cancer which is the most prominent feature ?

Answer 19

finger clubbing!!!

typically central

cavitating lesions are more common than other types

hypertrophic pulmonary osteoarthropathy (HPOA)

Question 20

x

Question 21

x

Question 22

x

Question 23

Large cell lung carcinoma features ?

Answer 23

typically peripheral

anaplastic, poorly differentiated tumours with a poor prognosis

Question 24

paraneoplastic features of large cell lung cancer ?

Answer 24

B - HCG

Question 25

paraneoplastic features of large cell lung cancer ?

Answer 25

B - HCG