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Flashcards in Lung Cancer Deck (24)
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1

TTF-1 (thyroid transcription factor) is expressed most characteristically in what type of carcinoma?

small cell and adenocarcinoma

2

P63 is expressed in what type of carcinoma?

squamous

3

What type of lung cancer is the worst?

small cell

4

What may often show K-ras mutation

lung adenocarcinomas

5

What is a tyrosine kinase inhibitor which shows activity in some NSCLC patients?

gefitinib

6

Which lung cancer is most common?

squamous

7

Which lung cancer is most deadly?

small cell

8

Where is small cell located?

across the hilium/central

9

Where are adenocarcinomas of the lung?

peripheral

10

Why do adenocarcinomas present late?

as they are peripheral, they are less likely to cause obstruction symptoms

11

Where are large cell lung cancers located?

centrally

12

Where are squamous cell lung cancers located?

centrally/ across large bronchi

13

How is lung cancer diagnosed?

bronchoscopy with biospy

14

Which type of lung cancer do smokers get?

squamous

15

Which type of lung cancer is known for hypercalcaemia?

squamous

16

What type of border of a cavity on a CT scan would suggest cancer?

jagged

17

What type of cancer causes signet rings?

adenocarcinoma

18

Which type of lung cancer is least likely to be related to smoking?

adenocarcinoma

19

Which type of lung cancer has early metastases?

small cell

20

Which type of lung cancer is gland forming on histology?

adenocarcinoma

21

Which has a poorer prognosis, large cell or squamous carcinoma?

large cell

22

Which type of lung cancer is very rare and may appear as consolidation on a CXR?

bronchoalveolar

23

Which type of lung cancer is extremely responsive to chemotherapy?

small cell

24

What type of cells do small cell lung cancers arise from?

endocrine (Kulchitsky) cells