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Flashcards in Therapeutics of Obstructive Airways Disease Deck (9)
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1

Which drugs are described as controllers in asthma?

Theophylline
Leukotriene-antagonist Increasing
Long-acting β2-agonist

2

What corticosteroids are used to treat asthma?

Prednisalone (orally) for ACUTE therapy
Beclomathasone (inhaled) for MAINTAINED therapy

3

What should be used in intermittent asthma?

SABA

4

What should be used in mild intermittent asthma?

SABA + inhaled steroid

5

What should be used in moderate to severe intermittent asthma?

SABA + inhaled steroid + LABA + LTRA/Theo

6

What are cromones e.g. cromoglycate and who are they effective in?

Mast cell stabiliser - weak anti-inflammatory compared to steroids
Useful in atopic children (exercise asthma)

7

How is cromoglycate delivered?

inhalationally

8

Describe treatment of acute asthma.

Oral prednisolone (or iv hydrocortisone )
•  Nebulised high dose salbutamol, ± Neb ipratropium, ± iv
aminophylline/magnesium
•  60% O2
•  ITU Assisted mecahnical intubated ventilation if falling
PaO2 and rising PaCO2
- never use respiratory stimulant

9

Describe treatment of acute COPD.

Nebulised high dose salbutamol + ipratropium
•  Oral prednisolone
•  Antibiotic (amoxycillin/doxycycline) if infection
•  24-28% O2 titrated against PaO2/PaCO2
•  Physio to aide sputum expectoration
•  Non invasive ventilation to allow higher FiO2
•  ITU Intubated assisted ventilation only if reversible
component (eg pneumonia)