Lung Development Flashcards
(6 cards)
1
Q
During which week of gestation does the embryonal stage begin development?
A
Fourth week (26 days)
Single lung bud divivdes into two primary bronchial buds
2
Q
Fill out your pneumonic for the stages of lung development are EPASA:
- E
- P
- A
- S
- A
A
Fill out your pneumonic for the stages of lung development are EPASA:
- Embryonal ==> 4 to 6 weeks
- Pseudoglandular ==> 6 weeks
- Acinar ==> 16 weeks
- Saccular ==> 28 weeks
- Alveolar ==> 34 weeks
3
Q
Identify the stage of lung development:
A
Embryonal Stage (26 days to 6 wks)
Proximal airways get it goin’
- Note the following:
- Esophagus
- Two primary lung buds
- Primitive mesenchyme
- The proximal lung basically completes development during this stage.
4
Q
Identify the stage of lung development:
A
Pseudoglandular (6 to 16 wks)
Bronchioles begin development
Timeline
- Pseudostratified columnar epithelium
- Cilia develop at 10-13 wks
- Goblet cells at 13-14 wks
- Submucosal glands at 15-16 wks
- Smooth muscle cells at 7 wks
- Lymphatics at 8-10 wks
- Cartilage at 4 wks
- Distinct rings around bronchi at 10 wks
5
Q
Identify the stage of lung development:
A
Acinar/Canalicular (16-29 wks)
Development and vascularization of acinus
- Pulmonary arteries come
- Note bronchioles surrounded by alveolar ducts
- Everything still separated by immature mesenchyme
- Early Type II cells are still fat/cuboidal
- Capillaries can be seen just beneath them
6
Q
Identify the stage of lung development:
A
Saccular (28-34 wks)