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Flashcards in Lung Development Deck (6)
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1

During which week of gestation does the embryonal stage begin development?

Fourth week (26 days)

Single lung bud divivdes into two primary bronchial buds

2

Fill out your pneumonic for the stages of lung development are EPASA:

  • E
  • P
  • A
  • S
  • A

Fill out your pneumonic for the stages of lung development are EPASA:

  • Embryonal ==> 4 to 6 weeks
  • Pseudoglandular ==> 6 weeks
  • Acinar ==> 16 weeks
  • Saccular ==> 28 weeks
  • Alveolar  ==> 34 weeks

3

Identify the stage of lung development:

Embryonal Stage (26 days to 6 wks)

Proximal airways get it goin'

  • Note the following:
    • Esophagus
    • Two primary lung buds
    • Primitive mesenchyme
       
  • The proximal lung basically completes development during this stage.

4

Identify the stage of lung development:

Pseudoglandular (6 to 16 wks)

Bronchioles begin development

 

Timeline

  • Pseudostratified columnar epithelium
  • Cilia develop at 10-13 wks
  • Goblet cells at 13-14 wks
  • Submucosal glands at 15-16 wks
  • Smooth muscle cells at 7 wks
  • Lymphatics at 8-10 wks
  • Cartilage at 4 wks
    • Distinct rings around bronchi at 10 wks

5

Identify the stage of lung development:

Acinar/Canalicular (16-29 wks)

Development and vascularization of acinus

 

  • Pulmonary arteries come
  • Note bronchioles surrounded by alveolar ducts
  • Everything still separated by immature mesenchyme

 

  • Early Type II cells are still fat/cuboidal
  • Capillaries can be seen just beneath them

6

Identify the stage of lung development:

Saccular (28-34 wks)