LUPUS

Question 1

most common form- can be mild or severe.

Answer 1

Systemic lupus erythematosus

Question 2

Lupus that is limited to skin and cause many types of rashes and lesions is known as _____. Can Also be called what?

Answer 2

Discoid lupus erythematosus (DLE)

cutaneous lupus erythematosus

Question 3

Autoimmune complexes tend to be attracted to ____of the kidneys

Answer 3

*glomeruli

Often kidney involvement

Question 4

Lupus makes the immune system unable to tell between ________(a substance capable of producing a certain immune
response) and ______. This leads the immune system to do what?

Answer 4

• antigens (a substance capable of producing a certain immune
• Healthy tissue
• attack healthy tissue not just the antigens,

Question 5

What 3 things does the lupus attack on healthy tissues cause?

Answer 5

swelling, pain, & tissue damage

Question 6

Hyperactivity of ____& disordered ______produces the autoantibodies

Answer 6

B-cells

T-cell function

Question 7

Majority of Lupus patients have some degree of _____involvement. ______ is the leading cause of death from the disease

Answer 7

• Kidney

* Lupus Nephritis

Question 8

Causes of LUPUS
Occurs more often (10x) in ______ (especially during _______)
ii. ____ predisposition
iii. Environmental factors (3 of them)
iv. Women ______ moreaffected, but also occurs in Native Americans, Asian Americans and Hispanics

Answer 8

• In women, especially in child bearing years (20-40)
• Genetic
• Smoking, sunlight, stress
• Women of color more effected

Question 9

_____criteria must be present in order to support a diagnosis of SLE

Answer 9

4 out of 11

Question 10

Which antibodies are tested for to diagnose lupus?

Answer 10

Anti-dsDNA and anti-sm antibodies – these antibodies are rarely seen in other conditions

Question 11

inflammation of the serous tissues of the body (the tissues that line the lungs, heart, abdomen, and inner abdominal organs)

Answer 11

Serositis

Question 12

Skin involvement in lupus? – dry, scaly, raised rash

Answer 12

dry, scaly, raised rash (butterfly rash), discoid lesions

Question 13

Skin manifestations only appear in _____of lupus patients…what are the two main ones

1. _____ or Butterfly Rash
2. Discoid Rash – stimulated by ____

Answer 13

30-40%

1. Malar (Butterfly rash)
2. Discoid Rash stimulated by UV light

Question 14

Assessment includes what 4 things?

Answer 14

*Psychosocial
Immunologic-based laboratory tests
*CBC (Often shows pancytopenia)
Body system function

Question 15

Treatment for lupus includes Anti-malarial- _____- decreases the absorption of _______, thus decreasing the risk for skin lesions. Teach patient to have frequent ______before starting the medication and _______months. Need baseline ____.

Answer 15

• Hydroxychloroquine (Plaqueni
• UV light by the skin
• Frequent Eye exams
• Every 6 months
• Base line EKG

Question 16

drugs-DLE-rash or discoid lesions-treat with topical _______.

Answer 16

cortisone preparations