Lupus Flashcards
(32 cards)
what triggers the onset of lupus
hormones (oral contraceptives, early onset menses, hormone replacement after menopause)
what can trigger lupus
exposure to some type of unknown virus, sunlight, UV light, or stress
discoid lupus
cutaneous, involves skin rash (may be butterfly or all over)
systemic lupus
attacks connective tissue, kidneys, and heart
drug induced lupus
can be caused by INH, thorazine (psych), apresoline (vasodilator), pronestyl (heart), and some anti-seizure meds
cause of anemia in lupus pts
during inflammatory process the body has a hard time replacing erythrocytes
swollen lymph glands in the area of rash
lymphadenopathy
sxs of pleural effusion
crackles, SOB, chest pain
C3 & C4 levels in lupus
decreased
BUN & creatinine in lupus
increased
urine: protein & RBC in lupus
positive
why do C3 & C4 go down
body can’t get rid of antigen/antibody complex
what helps bridge natural & acquired immunity
C3 & C4
pancytopenia
decrease in everything (WBC, platelet, RBC, etc)
sxs of pancytopenia
decreased cap refill, pallor, cold, blanchable
drugs for lupus (4)
NSAIDS, corticosteroids, immunosuppressants, anti-malarial
what levels should be monitored for drug induced hepatitis
ALT & AST
sxs of drug induced hepatitis
tired, lethargy, flu like sxs, N/V/D
what do NSAIDS do for lupus pts
decrease inflammation
what do corticosteroids do for lupus pts
decrease the inflammatory response
tx for peptic ulcer
proton pump inhibitor (prevacid, prilosec, pepsid)
what drug can cause peptic ulcer
corticosteroids
immunosuppressives
Methotrexate (Rheumatrex)
Azathioprine (Imuran)
side effects of immunosuppressives
alopecia, bone marrow suppression (formed elements of blood not made by bone marrow), increased infections, teratogenicity
