Lyme Disease - Bakken Flashcards Preview

Skin and Musculoskeletal - Week 3 > Lyme Disease - Bakken > Flashcards

Flashcards in Lyme Disease - Bakken Deck (12):
1

How long must a tick be attached in order to transfer the bacterial infection to the host?

36 hours (even then it's not even a sure thing)

2

Bacteria responsible for lyme disease?

B. Burgdorferi

3

Skin lesion indicative of lyme disease?

Erythema migrans (not all cases)

4

What types of symptoms do you see in early disseminated lyme disease?

Constitutional - EM lesions, lympadenopthy

Musculoskeletal - arthalgia, migratory arthritis

Neurologic - facial nerve palsy, radicular pain, poly neuritis

Cardiac - AV block

5

SYmptoms of late lyme disease?

Chronic arthritis
Acrodermatitis chronicum atrophicans
Neuro impairment

6

Lab tests used most commonly for confirming diagnosis?

ELISA + EIA to check for antibodies

PCR

7

Problems with serologic testing?

-Often get false positives
-IgG and IgM antibodies persist for years after initial infection
-Tests poorly standardized
-Absolute titer of Ab doesnt correspond to severity of infection

8

What would you need to make a lyme disease diagnosis?

History of exposure to Ixodes endemic area
History of tick bite
Clinical manifestations

Confirm using serology and PCR

9

What treatment do you use for early localized or systemic lyme disease?

Doxycycline
Amoxycillin
Cefuroxime

10

What drug can be used to treat both B. Burgdorferi and A. phagocytophilum?

Doxycycline can be used to treat both

11

What drug should you use to treat joint CNS and Cardiac Lyme Disease?

Arthritis and CNS Lyme
-use Doxycycline or ceftriaxone

Cardiac Lyme
-Use ceftriaxome

12

Is prophylactic doxycyline after a tick-bite important?

Probably not, just monitor well and treat as soon as any symptoms occur. Could be helpful though