Lymphatic and Immune System Flashcards

(55 cards)

1
Q

Which body system is responsible for adaptive immunity, consisting of lymph, lymphatic vessels, a number of structures and organs containing lymphatic tissues and red bone marrow

A

Lymphatic system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What type of specialized tissue makes the lymphatic system

A

Form of reticular connective tissue that contains large numbers of lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

After interstitial fluid passes into lymphatic vessels, it is called

A

Lymph

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The main difference of blood plasma and lymph interstitial fluid

A

interstitial fluid and lymph contain less protein than blood plasma because most plasma protein molecules are too large to filter through the capillary wall.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Each day, about how many liters of fluid filter from blood into tissue spaces.

A

20 L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

About how many liters of the fluid filtered daily from the arterial end of blood capillaries return to the blood directly by reabsorption at the venous end of the capillaries.

A

17 L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How many liters remain per day into lymphatic vessels and are then returned to the blood

A

3 L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Three Primary Functions of Lymphatic System

A
  • Drain excess interstitial fluid
  • Transport Dietary Lipids
  • Carries out immune responses
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What vitamins do the lymphatic system absorbed by the gastrointestinal tract into the blood

A

Vitamin K, A, D,E

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Where does the lymphatic vessels begin?

A

Lymphatic Capillaries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

When pressure is greater in interstitial fluid than in lymph, the cells do what?

A

separate slightly, like a one-way swinging door, and interstitial fluid enters the lymphatic capillary.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

When pressure is greater inside the lymphatic capillary, the cells

A

adhere more closely and lymph cannot escape back into interstitial fluid.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the two main channels of the lymph

A

The thoracic duct or the right lymphatic duct.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

The thoracic duct, the main lymph collecting duct, receives lymph from

A

the left side of the head, neck, and chest; the left upper limb; and the entire body below the ribs.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

The right lymphatic duct drains lymph from the

A

upper right side of the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What two pumps aid the return of venous blood to the heart to maintain the flow of lymph

A

Skeletal Muscle Pump

Respiratory Pump

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What do the Skeletal muscle pump

A

The “milking action” of skeletal muscle contractions compresses lymphatic vessels (as well as veins) and forces lymph toward the subclavian veins.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What do the Respiratory pump do?

A

1) Lymph flow is also maintained by pressure changes that occur during inhalation (breathing in).
2) Lymph flows from the abdominal region, where the pressure is higher, toward the thoracic region, where it is lower.
3) When the pressures reverse during exhalation (breathing out), the valves prevent backflow of lymph.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Primary Lymphatic Organs include:

A

(1) Red bone marrow - flat bones and the ends of the long bones of adults, where stem cells give rise to mature B Cells and immature T Cells.
(2) Thymus - T cells migrate to the thymus, where they mature into functional T cells. The Thymus is a two-lobed organ located posterior to the sternum. It contains large numbers of T cells and macrophages.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

The Secondary Lymphatic Organs include:

A
  • Lymph nodes, located along lymphatic vessels
  • The spleen is the largest single mass of lymphatic tissue in the body
  • Lymphatic Nodules
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What do lymph nodes do

A
  • Contain mature B cells, Plasma cells, T cells, dendritic cells, and
    macrophages.
  • Filter lymph, trap foreign substances (Macrophages & lymphocytes destroy most foreign substances)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What do spleens do

A

Contains two types of tissue

  1. white pulp (lymphatic tissue where B and T cells carry out immune responses)
  2. red pulp (blood-filled sinuses where worn-out blood cells and platelets are removed).
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What do lymphatic nodules do

A

They are plentiful in the connective tissue of mucous membranes lining the gastrointestinal, urinary, and reproductive tracts and the respiratory airways.

24
Q

What is Innate Immunity

A

Includes barriers provided by the skin and mucous membranes (First line of Defense) and also includes various internal defenses (Second line of Defense)

25
What is Adaptive Immunity
Involves lymphocytes called B cells and T cells and there are two types of adaptive immunity: Cell-mediated immunity and antibody-mediated immunity
26
What do PHagocytes do
specialized cells that perform phagocytosis. Thus the ingestion of microbes or other particles.
27
What do Natural killer cells do
These have the ability to kill a wide variety of microbes and tumor cells. They cause cellular destruction by releasing proteins that destroy the target cells membrane
28
What does Inflammation do
non-specific response of body to tissue damage. It prevents spread to other tissues and prepares site for repair.
29
What does Fever do
intensifies effects of interferons, inhibits microbial growth and speeds up reactions that aid in repair
30
What are the internal defenses?
``` Antimicrobial substances Phagocytes Natural Killer Cells Inflammation Fever ```
31
How does the skin and the mucous membrane protect themselves from microbes and bacteria?
Skin: Many layers of closely packed, keratinized cells, the epidermis and have continual shedding Mucous Membrane: Mucus is sticky and trapping microbes and foreign substances.
32
Lymphocytes, macrophages, and fibroblasts infected with viruses produce proteins called?
Interferons
33
What do interferons (IFNs) do when they are released?
Diffuse to uninfected neighboring cells, where they stimulate synthesis of proteins that interfere with viral replications
34
What is the process called when complement protein binds to the surface of a microbe and promote phagocytosis
Opsonization
35
What are short peptides that have a broad spectrum of antimicrobial activity?
Antimicrobial proteins
36
The four signs and symptoms of inflammation
Redness, pain, heat and swelling
37
What cells produce what fever causing substance
Macrophages and interleukin-1
38
What happens to the body when the body temperature intensifies
Effects of interferons, inhibits the growth of some microbes, and speeds up body reactions that aid repair
39
What are the characteristics of Innate immunity
- Not specifically directed against a particular type of invader
40
What is any substance such as microbes, foods, drugs, pollen, or tissue that the immune system recognizes as foreign
An antigen
41
What is the branch of science that deals with the responses of the body to antigens is ?
Immunology
42
What cells are involved with adaptive immunity
Lymphocytes called B cells and T cells
43
Where do B cells and T cells complete their development
B cells: Red bone marrow | T cells: Migrate from the red bone marrow to the thymus
44
What are the two major types of mature T cells that leave they thymus
Helper T cells and Cytotoxic T cells
45
What are the two types of adaptive immunity and what triggers them
Cell mediated immunity Antibody mediated immunity Both by antigens
46
What happens in cell mediated immunity
Cytotoxic T cells directly attack invading antigens
47
What happens in antibody mediated immunity
B cells transform into plasma cells, which synthesize and secretes specific proteins called antibodies A given antibody can bind to and inactivate a specific antigen
48
Cell mediated immunity is particularly effective against and how does it affect the way it attacks
1. INtracellular pathogens, including viruses, bacteria, fungi that are in the cell 2. Some cancer cells 3. Foreign tissue transplant Cells attacking cells
49
How does antibody mediated immunity works and what is referred as
Works mainly against Extracellular pathogens that are outside the body Humoral immunity
50
What is the process by which a lymphocyte proliferates and differentiates in response to a specific antigen
Clonal Selection
51
What are the two major types of cells in the clone that a lymphocyte undergoes during clonal selection
Effector and memory cells
52
What are included as effector cells and what do they do
Active T cells Active Cytotoxic T Cells Plasma Cells Carry out immune responses that ultimately results in the destruction or inactivation of the antigen
53
What do memory cells do and which cells are memory cells
- If the same antigen enters the body again in the future, they are available to initiate a far swifter reaction than the first invasion - Memory helper T cells - Memory cytotoxic T cells - Memory B Cells
54
What causes the body to produce specific antibodies and/or specific T cells that react with it
Antigen
55
What is located on the plasma membrane surface of most body cells that are protein "self antigens"
Major histocompatibility complex (MHC)