Lymphatic System Flashcards

(37 cards)

0
Q

What is lymph?

A

Fluid within lymphatic system

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1
Q

What are the 2 functions of the lymphatic system?

A

return interstitial fluid and leaked protein back into the blood
forms structural basis of immune system

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2
Q

The lymphatic system is a ________ system that carries blood to the heart.

A

One way

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3
Q

Where are lymphatic capillaries located?

A

between tissue cells and blood capillaries, in loose CT

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4
Q

What is the structure of lymphatic capillaries?

A

blind ended and more permeable than blood caps
lining = leaky endothelium
has overlapping edges which form valves

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5
Q

What do the tiny valves in lymphatic capillaries respond to?

A

they are one way

open and close in response to surrounding pressure

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6
Q

What is function of lymphatic caps?

A

collect excess interstitial fluid/proteins

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7
Q

What are lacteals?

Where found and what do they do?

A

Specialized lymph caps in villi of small intestine

absorb digested fats and deliver chyle to blood

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8
Q

Chyle?

A

fatty lymph

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9
Q
What are collecting vessels formed by?
What are the parallel with?
How do they compare to veins?
What are the branching vasa vasorum for?
When two join what do the form?
A
2nd smallest
joining of lymph caps
parallel to BV
thin walls
lots of valves and anastomoses
nutrient provision by branching vasa vasorum
join to form lymphatic trunks
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10
Q
How big are Lymphatic Trunks?
How are they formed?
What trunks drain into cistrna chyli?
What drains into upper body and head?
What do they join to form?
A
2nd largest
joining lymphatic collecting vessels
R&L lumbar trunks and intestinal
R&L bronchomediasinals, subclavian and jugulars
R& L Lymphatic Ducts
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11
Q

Where does the Right Lymphatic duct collect from?

where Does it drain into?

A

R upper arm and right head/ thorax

into junction of right internal jugular and subclavian Vein

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12
Q

Where does thoracic duct collect from?

Where does it drain into?

A

rest of body

into junction of left internal jugular and subclavian

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13
Q

How does lymph transport compare to venous?

What does its movement depend on?

A

slower, no pump(valves instead –> no backflow)

Contraction of skeletal/resp muscles
pulsation of arteries
contraction of smooth muscle in walls of trunks and thoracic duct

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14
Q

Lymphedema?

A

Swelling of tissues from blockage of flow, accumulates distally

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15
Q

What are examples of lymphoid cells?

A
Lymphocytes
B&T Cells
Macrophages
Dendritic Cells
Reticulare cells
16
Q

Where are lymphocytes formed?
What do they do?
What are they active in?
What are the 2 kinds?

A

Red bone marrow
defend against foreign antigens
immune defenses
B&T

17
Q

Where do B Cells Mature in? What do they produce?

A

Bone marrow

plasma Cells that form antibodies

18
Q

Where do T Cells Mature? What is their function in immune response? What are some capable of?

A

Thymus
Management of it
Attack and destroy cells directly

19
Q

What do Macrophages do?

A

phagocytize foreign antigens

activate T Cells

20
Q

What do dendritic Cells Do and How?

A

Activate defense (early warning system) by capturing antigens and delievering them to lymph nodes

21
Q

What do reticular cells form?

What does this produce?

A

internal skeleton

stroma which supports other cells

22
Q

What kind of tissue for Lymphoid?
What does Lymphoid tissue house and provide a site for?
Which lymphoid organ isn’t it found in?
What lives on its fibres?

A

reticular CT
lymphocyte survalience and multiplication
thymus
macrophages

23
Q

WWhat are the two Types of Lymphoid Tissues?

A

Diffuse and follicles

24
What kind of lymphoid tissue is found in most organs? | What does it include?
Diffuse Tissue | small scattered clusters of reticular tissue
25
What kind of tissue has solid spheres of reticular elements and cells with no capsule? It has germinal layers where ____ cells multiple and form plasma cells. What does this tissue form parts of?
Follicle Tissue B Lymph organs or scatters
26
What is a lymph node?
principal lymphoid organ. | Lie singly along lymph vessels or in clusters where vessels join forming trunks
27
What do macrophages do in the lymph node? | What about Lymphocytes?
Filter and remove foreign particles from lymph prevents spread and entrance of pathogens into blood Monitor and attack antigens activate immune system
28
What is the structure of a lymph node?
Bean shaped capsule of dense CT Trabeculae - divide nodes into compartments stroma (dense reticular fibers with attached cells) Cortex - (outer: follicles wrapped in dendritic cells and germinal cells for B cells) (deep Cortex:Tcells on patrol circulating continuously.) medullary cords - b/t/plasma cells Lymph Sinuses (house macrophages)
29
What is the circulation through a lymph node?
afferent vessels --> sub capsular sinus --> smaller sinuses --> exits via efferent @ hilus, slow flow due to fewer efferents than afferents Allows time for cleaning of lymph by macrophages and lymphocytes
30
What is the Spleen function in?
``` Lymphocyte proliferation/surveillance Cleans blood of debris/foreign Stores breakdown products of RBC Site of rbc in fetus stores blood platelets ```
31
What is Spleen enclosed in? (and thats characteristics) What cells does it contain? What types of pulp does it contain?
Capsule which has Trabeculae and sinuses, capsule is thin lymphocytes, macrophages RBC White Pulp - WBC , form cluster around central arteries Red Pulp - RBC 9venous sinuses and splenic cords
32
Bone marrow and liver take over functions?
splenectomy
33
What is thymus?
Primary Lymphoid organ in neck as age shrinks has two lobes divided into lobules Outer cortex contains T cells and scattered macrophages inner medulla - few lymphocytes, has hassall's corpuscles regulating T cell development Stroma is composed of thmocytes secreting thmosin and thymopoietin hormones stimulate T Cell Maturation no Bcells , no direct role in fighting antigens
34
Red Mone Marrow?
Primary lymphoid org, site of B cell maturation
35
What is simplest Lymphoid organ?
Tonsils have follicles with germinal centers producing B cells have crypts that trap and destroy matter important in early life
36
Aggregates of lymphoid Follicles(MALT)?
mucosal associated lymphoid tissue protects passages that open to outside from invaders many different memory cells generated.