Lymphedema Flashcards
Lymphedema
Chronic collection of high protein fluid just under the skin
Usually in one or both arms or legs
Areas of the body that do not have lymph vessels
Hair
Nails
Cornea
Cartilage
Lymph capillaries
Larger than blood capillaries Able to absorb large molecules from intersititium Simple squamous epithelium Overlapping ends Anchoring filaments
Lymph pre collectors
Connect lymph capillaries to lymph collectors
Can also absorb fluid
Lymph collectors
3-layer wall but thinner than vein
Valves
Made up of lymphangions
Extrinsic lymphangion contractions
Breathing Exercise Artery pulsation Vein negative pressure Compression on skin
Intrinsic lymphangion contractions
ANS (smooth muscle)
Lymph trunks and ducts
Collect and dump up into heart and veins
Most from thoracic duct into L venous angle
Lymph nodes
Kidney shaped
Filter lymph
Produce lymphocytes
Usually in adipose
Watersheds
Regions that drain to particular lymph nodes
Anastomoses
Connection b/n lymph collectors;
Across watersheds
Lymph system function
Return protein and fluid from interstitial to CV system
Absorbs fat and vitamins from small intestines —> CV system
Immune surveillance and functions
Filter fluid
Lymph system removes these from insterstitium
Protein Water Cell Fat Carbs, electrolytes, creatinine, urea, coagulation factors
Lymph time volume
Amount of fluid removed from intersititum per day
Normal 4L
Norm approx 10% of transport capacity
Transport capacity
Max amount of fluid lymphatic system can carry
Lymph functional reserve
Difference between normal lymph time volume and transport capacity
If system not running at transport capacity, lymph time volume can be increased to handle increased fluid
Increased lymph capillary filtration
Hypermedia from inflammation, massage, heat, CHF, DVT, tumor growth, venous insufficiency
Hypoproteinemia
Lymph system removes what percent of excess interstitial fluid?
90%
Lymph high output failure
Too much fluid for lymphatic system to return
Lymph low output failure
Damaged lymphatic system cant handle normal interstitial fluid
Combination lymph system failure
Lymph system damaged due to chronic conditions
Secondary lymphedema - damage
Surgery – mastectomy, prostate cancer removal,
hysterectomy, other • Cancer • Accident/injury • Infection • Radiation • In 3rd world countries: filariasis
Lymphedema secondary - overload
Obesity
• Chronic Venous Insufficiency
• Edema caused by cardiac, liver, or renal dysfunction
Primary lymphedema
Aplasia
• Hypoplasia
• Hyperplasia Believed to be present at birth, symptoms usually develop later