MALARIAL PARASITES (PLASMODIUM SPP)

Question 1

Sexual Phases

Answer 1

• Female Anopheles Mosquito (DH)
• Sporogony/Sporogonic Cycle

Question 2

Asexual Phase

Answer 2

• Man or other vertebrates (IH)
• Schizogony (Erythrocytic/Exo-Erythrocytic)
• Gametogony (Merogony)

Question 3

sleeping or dormant forms; causes relapse of the disease when reactivated

Answer 3

hypnozoites

Question 4

these reinvade the hepatocytes following rupture of schizont

Answer 4

vivax and ovale

Question 5

microgametocytes

male or female

Answer 5

male

Question 6

macrogametocytes

male or female

Answer 6

female

Question 7

age of RBC infected in P. falciparum

Answer 7

ALL

Question 8

age of RBC infected in P. vivax

Answer 8

Young

Question 9

age of RBC infected in P. ovale

Answer 9

Young (Retics)

Question 10

age of RBC infected in P. malariae

Answer 10

Mature

Question 11

appearance of parasitized RBC in P. falciparum

Answer 11

Normal; multiple
infection of RBC very
common

Question 12

Appearance of
parasitized RBC in P. vivax

Answer 12

Larger than normal,
pale, and oval to
normal in shape

Question 13

Appearance of
parasitized RBC P. ovale

Answer 13

Larger than normal,
oval and may have
fimbriated edges

Question 14

Appearance of
parasitized RBC P. malariae

Answer 14

Normal in shape; size
may be normal or
slightly smaller

Question 15

RBC stippling in P. falciparum

Answer 15

Maurer’s dot’s (occasionally seen)

Question 16

RBC stippling in P. vivax

Answer 16

Schuffer’s dots (commonly/routinely seen)

Question 17

RBC stippling in P. ovale

Answer 17

Schuffer’s/James dots

Question 18

RBC stippling in P. malariae

Answer 18

Ziemann’s dots rarely seen

Question 19

Stages in the peripheral blood P. falciparum

Answer 19

Rings, gametocytes

Question 20

Stages in the peripheral blood P. vivax, P. ovale, P. malariae

Answer 20

Rings, mature trophozoite (schizont gametocytes)

Question 22

Length of erythrocytic cycle in P. falciparum

Answer 22

36-48 hrs

Question 23

Length of erythrocytic cycle P. vivax

Answer 23

48 hrs

Question 24

Length of erythrocytic cycle P. ovale

Answer 24

48 hrs

Question 25

tertian malarias

Answer 25

P. falciparum, P. vivax, P. ovale

Question 26

Length of erythrocytic cycle P. malariae

Answer 26

72 hrs

Question 27

Length of erythrocytic cycle is based on what

Answer 27

paroxysm

Question 28

disease caused by P. falciparum

Answer 28

malignant tertian malaria

Question 29

black water fever

Answer 29

P. falciparum

Question 30

disease caused by P. vivax

Answer 30

Benign tertiary malaria

Question 31

disease caused by P. ovale

Answer 31

ovale tertian malaria

Question 32

disease caused by P. malariae

Answer 32

Quartan malaria

Question 33

true or false P. falciparum mature trophozoites and schizonts are rarely found in the peripheral blood because they are sequestered in the deep vasculature (small blood vessels of internal organs) where schizogony occurs.

Answer 33

true

Question 34

banana shaped Plasmodium

Answer 34

P. falciparum (unique)

Question 35

daisy formation of merozoites

Answer 35

P. malariae

Question 36

incubation period of malaria

Answer 36

8-40 days

Question 37

classical sign of malaria; characterized by chills, fever, and profuse sweating

Answer 37

paroxysm

Question 38

recurrence of paroxysm

Answer 38

periodicity

Question 39

every 24 hrs

Answer 39

Quotidian

Question 40

Quotidian Malaria

Answer 40

Plasmodium knowlesi

Question 41

Every 48 hrs

Answer 41

tertian malaria

Question 42

tertian malaria

Answer 42

P. falciparum, P. vivax, P. ovale

Question 43

Every 72 hrs

Answer 43

Quartan malaria

Question 44

Quartan malaria

Answer 44

P. malariae

Question 45

most fatal type caused by Plasmodium falciparum

Answer 45

Malignant tertian malaria

Question 46

manifestations of malignant tertian malaria

Answer 46

- black water fever - intravascular hemoglobinuria - from red urine to brown's black

Question 47

resistance to P. falciparum may be due to

Answer 47

sickle cell trait

Question 48

Fy (a-b-) resistance to P. vivax

Answer 48

Duffy negative blood group

Question 49

parasite of monkeys

Answer 49

Plasmodium knowlesi

Question 50

Simian/5th Human Malaria

Answer 50

Plasmodium knowlesi

Question 51

young P. knowlesi resembles __________; while mature forms resemble _______

Answer 51

P. falciparum; P. malariae

Question 52

relapse may occur with _______ infections due to reactivation of _________ in the liver

Answer 52

P. vivax and P. ovale; hypnozoites