Male Reproduction Flashcards Preview

Q3 Physio II Final > Male Reproduction > Flashcards

Flashcards in Male Reproduction Deck (41):
1

Testosterone fxns?

1) reg sperm gen
2) reg hypothal-pit-testes axis
3) 2º characteristics

2

Purpose of testes?

produce sperm
secrete testost

3

Accessory sex glands include?

Purpose?

seminal vesicles, prostate, bulbourethrals

secrete bulk of semen

4

Male reproductive tract includes?

Epididymis
Ductus deferens
Ejac duct

5

Testes descended by?

7th mo in utero

6

Testes compartments? (2)

1) Seminiferous tubules
2) CT

7

Seminiferous tubules purpose?

Made of what cell types? (2)

sperm gen

Germ cells
Sertoli cells

8

Germ cells purpose?

produce spermatogonia

9

Sertoli cells purpose? (5)

1) Form blood/testes barrier
2) Secrete antimull hormone, inhibin, androgen binding protein
3) Nourish germ cells
4) Secrete aqueous fluid to flush sperm
5) Phagocytize failed sperm

10

CT in testes made of what cell type?

Purpose?

Leydig cells

secrete testost

11

Spermatogenesis mediated by?

Takes how long?

testosterone

74 days

12

Spermatogenesis stage 1?

Mitosis (proliferation):
daugh cells divide into 4 primary spermatocytes

13

Spermatogenesis stage 2?

Meiosis (division):
Spermatocytes divide into spermatids

Yield of 16

14

Spermatogenesis stage 3?

Spermiogenesis (packaging/maturation):
Spermatids into spermatozoa (mature sperm)

Elongation
Remodeling of nucleus
Chromatin condensed
Cytoplasm lost
Acrosome formed

15

Spermiation is?

Spermatozoa moved from sertoli cells into tubule lumen ->
ducts into epididymis ->
myepith cell contraction moves into ductus deferens

16

Spermatogenic Wave is?

Continuous cycle of sperm prdxn:
rate constant (hormones Ø ∆ rate)

17

What hormones control sperm gen?

GnRH (pulsatile release)
FSH
LH

18

FSH purpose?

Sensitizes sertoli cells to testost
Promotes secretion of Inhibin/ABP

19

ABP purpose?

keep testost high in gonads

20

LH purpose?

↑ cholesterol desmolase activity -> stim leyding cells -> testost prdxn

21

FSH/LH regulated through?

neg feedback of testost and Inhibin

22

Testosterone fxns before birth?

reproductive tract and external genitalia

23

Testosterone sex-specific fxns after birth?

grow/matur reprod syst at puberty
maintain post puberty
sperm gen
gonadotropin secretion control

24

Testosterone non-reprod fxns?

protein anabolics
bone growth and closes plates

25

Testosterone produced by?

Leydig cells in testes

26

Testosterone kept in tubules by?

ABP from sertoli cells

27

Testosterone circulates in blood how?

w/ sex-hormone binding globulin

28

Testosterone can be ∆d to what at target tissues?

DHT or estradiol

29

Effects of steroid use?

↓ LH/FSH
↓ sperm gen
↑ free estrogen

30

Androgen Deficiency in Aging Males (ADAM) presentation?

↓ bone, mm, libido
↓ hct
↑ facial hair
∆ appetite

31

Semen prdxn in access organs?

seminal vesicle 60%
prostate 20%
bulbourethral 10%

32

Excitation phase?

PNS arteriole dilation via NO/Ach
↓ venous outflow
PNS stim bulbo for lube
Sensations transmitted via pudendal nn to sacral plexis

33

Plateau phase?

↑ responses
ANS activity (↑ HR/BP/resp/mm tension)

34

Erection caused by?

PNS stim of S2-4 to penis
NO relaxes helicine aa -> allows blood to engorge

35

Erectile tissues?

Corpora cavernosa w/ central aa
Corpus spongiosum

36

Plateau phase female only?

More vasocongestion
Tenting of cervix

37

Ejaculation caused by?

SNS stim of L1-2

Emission: fluid into urethra, smooth mm/access gland contraction

Expulsion: full urethra stim skeletal mm at base

38

Ejac pathway?

vas deferens -> ejac duct (ampula) -> urethra

39

ED tx?

phosphodiesterase inhib -> ↑ NO relax of smooth mm

prostaglandin injections

40

Endocrine male contraceptives?

desotrogestrel/etonogestrel (synth progestin) + testost

severe oligoazoospermia

41

Intra Vas device?

silicone plug in vas def