Management

Question 1

What is the gold standard investigation for bacterial STIs?

Answer 1

Culture from urethral/rectal smear

Question 2

What is the gold standard investigation for TB?

Answer 2

3 Sputum Samples
Ziehl-Neelson Stain
Lowenstein-Jensen Medium

Question 3

What is the gold standard diagnostic test for Acromegaly?

Answer 3

OGTT

Question 4

What is the gold standard investigation for Coeliac?

Answer 4

Upper GI endoscopy and distal duodenal biopsy

Question 5

What is the gold standard investigation for food/drug allergy?

Answer 5

Double-Blind Oral Challenge

Question 6

What is the gold standard investigation for breast cancer?

Answer 6

Histopathology

Question 7

What is the first line treatment for Hospital-Acquired Pneumonia?

Answer 7

Ciprofloxacin + Vancomycin

Question 8

What is the treatment for severe HAP?

Answer 8

Tazocin + Vancomycin

Question 9

What is the treatment for aspiration pneumonia?

Answer 9

Tazocin + Metronidazole

Question 10

What is the treatment for CURB 0/1 CAP?

Answer 10

Amoxicillin

Question 11

What is the treatment for CURB 2 CAP?

Answer 11

Amoxicllin

Clarithromycin

Question 12

What is the treatment for CURB 3-5 CAP?

Answer 12

Co-Amoxiclav

Clarithromycin

Question 13

What is the first line management for Minimal Change disease?

Answer 13

Steroids

Question 14

What is the second line management for Minimal Change Disease?

Answer 14

Cyclosporin

Question 15

What is the first line agent for CMV?

Answer 15

Ganciclovir

Question 16

How is EBV managed?

Answer 16

Supportive

Question 17

How is VZV managed?

Answer 17

Aciclovir

Question 18

How is HSV managed?

Answer 18

Aciclovir

Question 19

What is the first line management for myeloma?

Answer 19

Bortezomib

Question 20

How is Salmonella treated?

Answer 20

Ceftriaxone

Question 21

How is Campylobacter treated?

Answer 21

Erythromycin/Ciprofloxacillin

Question 22

How is Listeria treated?

Answer 22

Ampicillin

Question 23

How are Entamoeba histolytica/Giardia lamblia treated?

Answer 23

Metronidazole

Question 24

How is Cryptosporidium Parvum managed?

Answer 24

Paromomycin

Question 25

When would you consider transfusing red blood cells?

Answer 25

<70 if asymptomatic | <80 if symptomatic

Question 26

How is Dengue Fever managed?

Answer 26

Supportive

Question 27

How is DKA managed?

Answer 27

A to E 0.9& Saline Fixed rate IV insulin after fluids Monitor Glucose & K+

Question 28

How is HHS managed?

Answer 28

A to E 0.9% Saline Fixed rate IV Insulin

Question 29

How would you manage a surgical wound infection with Staph a?

Answer 29

Fluclox

Question 30

How is syphilis treated?

Answer 30

Single dose IM Benzylpenicillin

Question 31

How is TB treated?

Answer 31

Rifampicin Isoniazid Pyrazinamide Ethambutol

Question 32

How is cryptococcal meningitis treated?

Answer 32

Amphotericin B

Question 33

How would you manage MGUS/Smouldering Myeloma?

Answer 33

No treatment needed

Question 34

How would you treat gonorrhoea?

Answer 34

IM Ceftriaxone

Question 35

What are the 5 steps for suspected Diabetes Insipidus?

Answer 35

``` Glucose K Ca Plasma/Urine Osmolality 8 Hour water deprivation test ```

Question 36

How is nephrogenic diabetes insipidus treated?

Answer 36

Thiazide Diuretics

Question 37

What is the only curative treatment for myelofibrosis?

Answer 37

Stem Cell Transplant

Question 38

How is HIV treated in pregnancy?

Answer 38

Zidovudine (NRTI)

Question 39

How is Digoxin toxicity treated?

Answer 39

Digibond

Question 40

How would you treat hypokalaemia 3.0-3.5?

Answer 40

Oral KCl

Question 41

How would you treat Hypokalaemia <3.0?

Answer 41

IV KCl

Question 42

When would you treat Hyperkalaemia?

Answer 42

>5.5 and ECG changes | >6.5 regardless

Question 43

How would you treat Hyperkalaemia?

Answer 43

``` Calcium Gluconate Dextrose + Insulin Nebulised Salbutamol Maybe Calcium Resonium Treat Cause ```

Question 44

How would you treat Carcinoid Syndrome?

Answer 44

Octeotride (Somatostatin Analogue)

Question 45

Which factors' synthesis is inhibited by Warfarin?

Answer 45

2,7,9,10 | C,S,Z

Question 46

Which factors does heparin inhibit?

Answer 46

Thrombin | 9,10,11

Question 47

How would you manage someone with Vitamin K Deficiency who is acutely haemorrhaging?

Answer 47

Fresh Frozen Plasma

Question 48

How might Myasthenia Gravis be treated?

Answer 48

Neostigmine

Question 49

Which drugs may be used to treat small/medium vessel vasculitides?

Answer 49

Corticosteroids | Cyclophosphamide

Question 50

How is Hodgkin's Lymphoma treated?

Answer 50

``` ABVD Adriamycin Bleomycin Vinblastine Dacarbazine ```

Question 51

How is chronic granulomatous disease treated?

Answer 51

IFN-gamma

Question 52

How is AML treated?

Answer 52

Daunorubicin | Cytarabine

Question 53

Which drug targets diseases with a (9;22) translocation?

Answer 53

Imatinib

Question 54

How is Burkitt's Lymphoma treated?

Answer 54

Rituximab (Anti-CD20)

Question 55

How is Acute Rheumatic fever treated?

Answer 55

Benzylpenicillin

Question 56

Name one agent which may be used in the treatment of Sideroblastic Anaemia?

Answer 56

Pyridoxine

Question 57

How is Addison's Treated?

Answer 57

Hormone replacement

Question 58

How is Haemochromatosis treated?

Answer 58

Venesection | Desferrioxamine

Question 59

How is Wilson's treated?

Answer 59

Zinc + Trientine > Penicillamine

Question 60

How might Multiple Sclerosis be treated?

Answer 60

Corticosteroids Interferon Beta Natalizumab

Question 61

How might you manage Goodpasture's?

Answer 61

Plasmapheresis

Question 62

How would you manage Kostmann Syndrome?

Answer 62

Colony stimulating factor