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236 - Dementia > Management > Flashcards

Management Flashcards

(12 cards)

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1
Q

When would you use acetylcholineesterase inhibitors?

A

Alzheimers

Lewy body dementia

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2
Q

What are some examples of acetylcholineesterase inhibitors?

A

Donepezil

Rivastigmine

Galantamine

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3
Q

What are some side effects of acetylcholineesterase inhibitors?

A

Bradycardia

Bladder outflow restriction

Restlessness/agitation

GI irritation

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4
Q

What is the NMDA receptor antagonist and when would you use it?

A

Memantine

Alzhemers where acetylcholineesterase inhibitors contraindicated or in severe disease

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5
Q

How does memantine work?

A

Reduced glutamate excitotoxic effects

When the cells die they release glutamate which causes calcium influx in adjacent cells and their resultant death - like a chain reaction

Memantine stops this

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6
Q

What are the side effects of memantine?

A

Cons

HTN

Dyspnoea

Headache

DIzziness

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7
Q

What is the treatment for vascular dementia

A

Modify risk factors - Aspirin

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8
Q

When would you use anti parkinsonian medication?

A

Lewy body dementia

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9
Q

What do antipsychotics increase the risk of?

A

Stroke

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10
Q

What antipsychotic could be used?

A

Risperidone

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11
Q

Why is using antipsychotics controversial?

A

Increase risk of stroke and need to weigh up the risks/benefits

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12
Q

What other medications can be used for dementia?

A

SSRIS

Sedation for sleep - Zopiclone

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236 - Dementia (4 decks)

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