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Biochimica Clinica > Marcatori Tumorali > Flashcards

Marcatori Tumorali Flashcards

1
Q

ALP

A

Enzimi
Fosfatasi alcalina,
tumore epatico e metastasi ossee

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2
Q

LDH

A

Enzimi
Lattico deidrogenasi,
5 isocore per vari tessuti, epatomi linfomi leucemie

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3
Q

CK

A

Enzimi
Creatinchinasi
Tumori prostatici e microcitomi polmone
Danneggiamento muscolare

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4
Q

NSE

A

Enzimi
Enolasi neurone specifica
Tumori neuroendrocrini

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5
Q

PSA

A

Enzimi
Antigene prostatico specifico
Rapporto PSA libero / PSA totale

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6
Q

Calcitonina

A

Ormoni
Cellule C tiroide
Carcinoma tiroide o broncogenico

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7
Q

hCG

A

Ormoni
Gonadotropina corionica umana
Tumori testicoli
Gravidanza

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8
Q

PTHrP

A

Ormoni
Peptide associato all ormone paratiroideo
Ipercalcemia associata al cancro o
ridotta funzionalità renale

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9
Q

Recettori estrogeni e progesterone

A

Selezionare chi avendo tumore alla mammella potrà rispondere a terapia neuroendocrina

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10
Q

AFP

A

Proteine onco fetali carcino embrionarie
Alfa fetoproteina
Epatocarcinoma primario
Tumore cellule germinali

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11
Q

CEA

A

Proteine onco fetali carcino embrionarie
Antigene carcino embrionario
Tumori vari colon pancreas mammella polmoni
Fumatori ne hanno il doppio
Emivita lunga

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12
Q

PTA

A

Proteine onco fetali
Antigene polipeptidico tissutale
Utile per diagnosi differenziale
Gravidanza e malattie infiammatorie

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13
Q

SCC

A

Proteine onco fetali
Antigene carcinoma cellule squamose
Tumore cervice uterina e insufficienza renale

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14
Q

CA 125

A

Marcatori mucinici
Soglia 35 U/mL
Associato a HE4 human epididimus Protein da carcinoma ovarico o endometriale
Aspecifico può indicare anche solo infiammazioni o gravidanza o mestruazioni

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15
Q

CA 72-4

A

Mucinici
Tumori stomaco specifico
Recidive

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16
Q

CA 15-3

A

Mucinici
Adenocarcinoma mammella
51 U/mL

17
Q

CA 19-9

A

Mucinici
Tumori fegato
Aspecifico

18
Q

HE 4

A

Mucinici
Human epididimus protein 4
Associato a CA125 carcinoma ovarico o endometriale

19
Q

CAM

A

Molecole di adesione cellulare
Contribuiscono alla crescita cellulare e formazione di metastasi
Caderine selectine integrine immunoglobuline

20
Q

Fattori angiogenetici

A

Formazione vasi sanguigni
Fattori crescita fibroblasti
Angiogenine
Fattori crescita trasformanti alfa e beta

21
Q

Beta 2 microglobulina

A

Catena leggere antigene MHC I
Malattie linfoproliferative leucemie e linfomi
Emivita lunga

22
Q

Cromogranina A

A

Granuli cromaffini cellule midollari sure e
Feocromocitoma carcinoma polmone a piccole cellule

23
Q

CYFRA 21 1

A

Carcinoma e cellule squamose polmone

24
Q

CA 72 -4

A

Mucinici
Tumore stomaco specifico
Recidive

25
Q

CA 15-3

A

Mucinici
Adenocarcinoma mammella
51 U/mL

26
Q

CA 19-9

A

Mucinici
Tumori fegato aspecifico

27
Q

HE 4

A

Human epididimus protein 4
Associato a CA 125 carcinoma ovarico o endometriale

Biochimica Clinica (12 decks)

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