Maternal Physio - Endo Flashcards Preview

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Flashcards in Maternal Physio - Endo Deck (14):
1

T/F. Pituitary gland enlarges during pregnancy

Enlarges by approximately 135%

2

T/F. Growth hormone is essential for maintenance of pregnancy

False; GH is not essential for maintenance of pregnancy

3

Source of GH

  • First trimester
  • At 17 weeks AOG

  • First trimester
    • Secreted predominantly from maternal pituitary gland
  • At 17 weeks AOG
    • Placenta (syncitiotrophoblast) is the principal source

4

T/F. Fetal growth progresses in the complete absence of placental GH

True

5

Is prolactin production increased or decreased during pregnancy?

Increased; estrogen stimulation increases the number of APG lactotrophs

6

Hormone that inhibits prolactin secretion

Dopamine

 

Memory aid:

  • DOPamine
    • Dopamine
    • Oppresses
    • Prolactin

7

Prevent water transfer from fetus into the maternal compartment to prevent fetal dehydration

  • Hormone
  • Produced by

  • Hormone
    • Prolactin in amniotic fluid
  • Produced by
    • Uterine decidua

8

What happens to thyroid hormone production? What is the mechanism?

  • Increased by 40 to 100% to meet maternal and fetal needs
  • In response to high estrogen levels, pregnant women have elevated TBG and therefore will have elevated total thyroxine and T3

9

What happens to thyroid-releasing hormone in pregnancy?

  • Not increased
  • Crosses the placenta and may stimulate the fetal pituitary to secrete thyrotropin

10

PTH level in pregnancy

↓ in first trimester but then rise progressively the remainder of the pregnancy

11

Effect of estrogen in PTH and consequence

Estrogens block the action of parathyroid hormone on bone resorption, resulting in ↑ hormone levels, which allow the fetus to have adequate calcium supply

12

Allows for bone deposition in fetus

The fetus has ↑ calcitonin levels

13

Increased adrenal gland secretion

  • Cortisol
  • Aldosterone
  • Deoxycortisone
  • Androstenedione
  • Testosterone

14

Decreased adrenal gland secretion

DHEA-S

 

Memory aid:

  • DHEAcreased