Maternal Physio - Endo Flashcards Preview

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Flashcards in Maternal Physio - Endo Deck (14)
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1
Q

T/F. Pituitary gland enlarges during pregnancy

A

Enlarges by approximately 135%

2
Q

T/F. Growth hormone is essential for maintenance of pregnancy

A

False; GH is not essential for maintenance of pregnancy

3
Q

Source of GH

  • First trimester
  • At 17 weeks AOG
A
  • First trimester
    • Secreted predominantly from maternal pituitary gland
  • At 17 weeks AOG
    • Placenta (syncitiotrophoblast) is the principal source
4
Q

T/F. Fetal growth progresses in the complete absence of placental GH

A

True

5
Q

Is prolactin production increased or decreased during pregnancy?

A

Increased; estrogen stimulation increases the number of APG lactotrophs

6
Q

Hormone that inhibits prolactin secretion

A

Dopamine

Memory aid:

  • DOPamine
    • Dopamine
    • Oppresses
    • Prolactin
7
Q

Prevent water transfer from fetus into the maternal compartment to prevent fetal dehydration

  • Hormone
  • Produced by
A
  • Hormone
    • Prolactin in amniotic fluid
  • Produced by
    • Uterine decidua
8
Q

What happens to thyroid hormone production? What is the mechanism?

A
  • Increased by 40 to 100% to meet maternal and fetal needs
  • In response to high estrogen levels, pregnant women have elevated TBG and therefore will have elevated total thyroxine and T3
9
Q

What happens to thyroid-releasing hormone in pregnancy?

A
  • Not increased
  • Crosses the placenta and may stimulate the fetal pituitary to secrete thyrotropin
10
Q

PTH level in pregnancy

A

↓ in first trimester but then rise progressively the remainder of the pregnancy

11
Q

Effect of estrogen in PTH and consequence

A

Estrogens block the action of parathyroid hormone on bone resorption, resulting in ↑ hormone levels, which allow the fetus to have adequate calcium supply

12
Q

Allows for bone deposition in fetus

A

The fetus has ↑ calcitonin levels

13
Q

Increased adrenal gland secretion

A
  • Cortisol
  • Aldosterone
  • Deoxycortisone
  • Androstenedione
  • Testosterone
14
Q

Decreased adrenal gland secretion

A

DHEA-S

  • Memory aid:*
  • DHEAcreased