MBChB List Doses Flashcards
(353 cards)
1
Q
Acyclovir for genital herpes simplex suppression
A
400 mg bd
2
Q
Acyclovir for nongenital herpes simplex treatment
A
200 mg 5x 5/7
3
Q
Acyclovir for first-episode genital herpes simplex treatment
A
200 mg 5x
4
Q
Acyclovir for recurrent genital herpes simplex
A
800 mg tds 2/7
5
Q
Acyclovir for Varicella zoster/Herpes Zoster treatment in adults
A
800 mg 5x 7/7
6
Q
Acyclovir for Herpes Zoster/Varicella-Zoster encephalitis
A
10 mg/kg
every 8 hours
10-14 days
7
Q
Adrenaline for CPR
A
1 in 10 000
1 mg Q3-5 minutes IV
8
Q
Adrenaline for Acute anaphylaxis
A
500 micrograms IM Q5 minutes
9
Q
Alendronate for postmenopausal osteoporosis
A
10 mg OD
70 mg once weekly
10
Q
Alendronate for the treatment of osteoporosis in men
A
10 mg OD
11
Q
Alendronate for prevention/treatment of corticosteroid-induced osteoporosis in postmenopausal women
A
10 mg OD
12
Q
Allopurinol for gout prophylaxis (initial dose)
A
100 mg OD
13
Q
Allopurinol for gout prophylaxis (maintenance in mild gout)
A
100-200 mg OD
14
Q
Allopurinol for gout prophylaxis (maintenance in moderately severe gout)
A
300-600 mg divided doses
15
Q
Allopurinol for gout prophylaxis (maintenance in severe gout)
A
700- 900 mg OD
16
Q
Amiodarone for treatment of arrhythmias
A
200 mg tds 7/7 then 200 mg bd 7/7 then 200 mg OD
17
Q
Amiodarone for CPR (VF, pulsless VT refractory to defibrillatrion)
A
300 mg IV
18
Q
Augmentin for beta-lactamase-producing strains
A
250/125 mg Q8h
IV 1.2g Q8
19
Q
Augmentin for acute diverticulitis
A
500/125 mg tds 5/7
IV 1.2 g Q8h
20
Q
Augmentin for a diabetic foot infection
A
500/125 mg Q8
1.2g Q8h
21
Q
Augmentin for leg ulcer infection
A
500/125 mg Q8 7/7
IV 1.2 g Q8h
22
Q
Augmentin for cellulitis/erysipelas
A
500/125 mg Q8h 7/7
IV 1.2g Q8h
23
Q
Augmentin for surgical prophylaxis
A
IV 1.2 g 30 minutes before then Q8h for 2-3 doses in high-risk procedures
24
Q
Augmentin for community-acquired pneumonia
A
500/125 tds 5/7
IV 1.2g Q8
25
Augmentin for hospital-acquired pneumonia
500/125 mg tds 5/7
26
Augmentin for acute exacerbation of bronchiectasis
500/125 mg tds 7-14/7
| 1.2g Q8h
27
Augmentin for acute exacerbation of COPD
500/125 mg tds 5/7
| IV 1.2 g Q8h
28
Augmentin for acute sinusitis
500/125 mg tds 5/7
29
Augmentin for pyelonephritis/catheter-associated UTI
500/125 mg tds 7-10/7
| IV 1.2g Q8h
30
Aspirin for secondary prevention of CVD
75 mg OD
31
Aspirin for management of NSTEACs or STEMI
300 mg OD until dx established
32
Aspirin for long term treatment of TIA/ischemic stroke not associated with AF
75 mg OD
33
Aspirin for treatment of acute ischaemic stroke
300 mg OD for 14 days
34
Aspirin for mild to moderate pain
300 to 900 mg Q4-6h
| Max 4g/day
35
Aspirin for acute migraine
900 mg OD
36
Aspirin for prevention of Pre-eclampsia
75-150 mg OD from 12/40 until birth
37
Aspirin for Mild to moderate pain
300-600 mg Q4-6h max 2.4g/day
38
Atenolol for Hypertension
25-50 mg OD
39
Atenolol for Angina
100 mg daily
40
Atenolol for arrhytmias
50-100 mg OD
41
Atenolol for migraine prophylaxis
50 to 200 mg
42
Atropine for bradycardia due to beta blocker OD
3mg
43
Atropine for insecticide or nerve agent poisoning
2 mg Q5-10 minutes
44
Atropine for GI symptoms secondary to smooth muscle spasm
0.6- 1.2 mg nocte
45
Beclomethasone for asthma prophylaxis
200-400 mcg bd
| can go to 800 mcg
46
Beclomethasone for rhinitis
100 mcg bd
to 50 mcg
max 400 mcg
47
Bendroflumethiazide for oedema
5-10 mg OD then 5-10 mg 1-3 times a week
48
Bendroflumethiazide for hypertension
2.5 mg OD mane
49
Benztropine for medication-induced movement disorder
1-4 mg OD or BD
50
Benztropine for parkinsonism
0.5 to 1 mg increase in 0.5 increments at 5-6 day intervals (1-2 mg OD)
Max 6 mg/day
51
Benzylpenicillin for infections
0.6 to 1.2 g Q6h IM/IV
52
Benzylpenicillin for Endocarditis
1.2g Q4h
53
Benzylpenicillin for anthrax
2.4g Q4h
54
Benzylpenicillin for GB prophylaxis in labor
3g then 1.5g Q4
55
Benzylpenicillin for meningicoccal disease
2.4 g Q4h IV
56
Benzylpenicillin for suspected meningicoccal disease
1.2 g IV/IM before transfer
57
Bezafibrate for mixed hyperlipidaemia if statin contraindicated or not tolerated
200 mg tds
| SR 400 mg OD
58
Budesonide for prophylaxis of mild to moderate asthma
200-400 mcg OD
59
Budesonide for asthma prophylaxis
100-800 mcg BD
60
Budesonide for rhinitis
128 mcg OD
| 64 mcg BD
61
Budesonide for nasal polyps
100 mcg BD for 3/12
62
Carbamazepine for tonic-clonic seizures
100 to 200 mg 1-2x increased in steps of 100-200 mg every 2 weeks
usual dose 0.8 to 1.2 g daily
63
Carbamazepine for trigeminal neuralgia
100 mg 1-2x up to 200 mg 3-4 times
64
Carbamazepine for Bipolar prophylaxis unreponsive to lithium
400-600 mg
65
Carbamazepine for diabetic neuropathy
100 mg 1-2x increase to response
| to 200 3-4 x
66
Carbimazole for hyperthyroidism
15-40 mg OD till euthyroid
67
Cefazolin for surgical prophylaxis
1 g 30-60 minutes before then 0.5-1g during
68
Cefazolin for skin, bone, and joint infection
1-2 g daily
69
Cetirizine for allergy relief
10 mg OD
70
Colecalciferol for prevention of vitamin D deficiency
400 units OD
71
Colecalciferol for treatment of vitamin D deficiency
800 units OD
72
Ciprofloxacin for Acute otitis externa
0.25 mL bd 7/7
73
Ciprofloxacin for moderate to severe diabetic foot disease
500 mg BD
| IV 400 mg Q8-12h over 60 minutes
74
Ciprofloxacin for fistulating Crohns disease
500 mg BD
75
Ciprofloxacin for respiratory tract infections
500 to 750 mg BD
| 400 mg Q8-12h over 60 minutes
76
Ciprofloxacin for Pseudomonal LRTI in CF
750 mg BD
77
Ciprofloxacin for UTI
250-750 mg BD
| IV 400 mg Q8-12h over 60 minutes
78
Ciprofloxacin for prostatitis
500 mg BD 14/7
| IV 400 mg Q8-12h
79
Ciprofloxacin for uncomplicated gonorrhea
500 mg One dose
80
Ciprofloxacin for disseminated gonococcal infection
IV 500 mg Q12h 7/7
| PO 500 mg BD following IV treatment
81
Ciprofloxacin for infections
500 to 750 mg BD
| IV 400 mg Q8-12h over 60 minutes
82
Ciprofloxacin for Surgical prophylaxis
750 mg 60 minutes before
83
Ciprofloxacin for anthrax
500 mg BD
| IV 400 mg Q12h over 60 minutes
84
Ciprofloxacin for acute pyelonephritis/catheter-associated UTI
500 mg BD 7/7
| IV 400 mg Q8-12h
85
Clopidogrel for prevention of atherothrombotic events in PCI
300 mg loading dose
86
Clopidogrel for cerebrovascular event and contraindication to aspirin
75 mg OD
87
Clopidogrel for prevention of atherothrombotic event in PVD or following MI/stroke
75 mg OD
88
Clopidogrel for prevention of atherothrombotic event in NSTEMI
300 mg then 75 mg OD up to 12/12
89
Clopidogrel for prevention of atherothrombotic event in STEMI
300 mg then 75 mg
| >76 yo 75 mg for at least 4 weeks
90
Clopidogrel for prevention of atherothrombotic event in patients with AF and cannot take warfarin
75 mg OD
91
Codeine for acute diarrhea
30 mg 3-4x
| usual dose 15-60 mg 3-4x
92
Codeine for mild to moderate pain
30-60 mg Q4h max 240 mg
| IM 30-60 mg Q4h
93
Colchicine for Acute gout
500 mg 2-4x
| max 6g
94
Colchicine for short term prophylaxis of gout
500 mg bd
95
Cyclizine for nausea, vomiting, vertigo, motion sickness, labyrinthine disorders
50 mg up to 3x
| IV 50 mg tds
96
Cyclizine for nausea and vomiting in palliative care
150 mg SC
| 50 mg up to 3x
97
Dabigatran for VTE prophylaxis following knee replacement
110 mg 1-4 hours after surgery, 220 mg OD 10/7
| >75 yo 75 mg 1-4 hours after surgery then 150 mg OD for 10/7
98
Dabigatran for VTE prophylaxis following hip replacement
110 mg 1-4 hours after surgery,
220 mg OD 28-35/7
>75 yo
75 mg 1-4 hours after surgery
then 150 mg OD for 28-35/7
99
Dabigatran for treatment of DVT, OE
150 mg bd
>75 110-150 mg BD
>80 110 mg bd
100
Dabigatran for stroke/embolism prophylaxis in non-valvular AF
150 mg bd
>75 110-150 mg bd
>80 110 mg bd
101
Dexamethasone for suppression of allergic/inflammatory disorders
0.5-10 mg OD
102
Dexamethasone for mild croup
Child
| 150 mcg/kg
103
Dexamethasone for severe croup
Child
150 mcg/kg
then 150 mcg/kg IV
then 150 mcg/kg IV if needed
104
Dexamethasone for bacterial meningitis
IV 8.3 mg Q6h 4/7
105
Dexamethasone for cerebral edema
8-16 mg then 5 mg IM or IV Q6h
106
Diazepam for muscle spasm
2-15 mg daily
107
Diazepam for acute muscle spasm
IM/IV 10 mg then 10 mg ater 4 hours
108
Diazepam for tetanus
IV 100-300 mg/kg Q1-4h
109
Diazepam for anxiety
2 mg tds then 15-30 mg if needed
| 1 mg tds for elderly
110
Diazepam for insomnia and anxiety
5-15 mg OD nocte
111
Diazepam for severe anxiety/panic attack/acute alcohol withdrawal
10 mg the 10 mg after 4 hours IV/IM
112
Diazepam for status epilepticus
10 mg then 10 mg after 10 minutes at 1 mL per minute
113
Diclofenac for pain and inflammation in rheumatic/MSK disorders
75-150 mg in 2-3 doses
114
Diclofenac for acute gout
75-150 mg in 2-3 doses
115
Diclofenac for postoperative pain
75-150 mg in 2-3 doses
116
Diclofenac for migraine
```
50 mg at the onset of migraine
then
50 mg after 2 hours
then 50 after 4-6 hours
max 200 mg
```
117
Digoxin initial dose for atrial fibrillation or flutter
0.75-1.5 mg over 24 hours
118
Digoxin maintenance dose for AF or flutter
125 to 250 mcg
119
Digoxin for heart failure
62.5-125 mcg OD
120
Digoxin in emergency AF or flutter
the loading dose of 0.75-1 mg over 2 hours
121
Diltiazem for angina
60 mg tds max 360 mg/day
| elderly 60 bd max 360 mg/day
122
Docusate sodium for chronic constipation
up to 500 mg in divided doses
| PR 120 mg
123
Domperidone for nausea and vomiting
>35 kg weight
10 mg up to 3x
max 30 mg
124
Doxycycline for chlamydia, rickettsia, mycoplasma
200 mg in 1-2 doses then 100 mg OD
125
Doxycycline for severe infections
200 mg OD
126
Doxycycline for acute sinusitis, cough, community-acquired pneumonia
200 mg one dose
| then 100 mg OD 5/7
127
Doxycycline for hospital-acquired pneumonia
200 mg 1 dose then 100 mg OD 5/7
128
Doxycycline for acute exacerbation of bronchiectasis
200 mg for one dose, then 100 mg OD 7-14/7
129
Doxycycline for acute exacerbation of COPD
200 mg for 1 dose then 100 mg OD 5/7
130
Doxycycline for mild diabetic foot infection
200 mg for 1 dose then 100 mg OD for 7/7
131
Doxycycline for Cellulitis/erysipelas
200 mg for 1 dose the 100 mg OD for 5-7/7
132
Doxycycline for leg ulcer infection
200 mg for 1 dose
| then 100 mg OD for 7/7
133
Doxycycline for acne
100 mg OD
134
Doxycycline for rosacea
100 mg OD
135
Doxycycline for early syphilis
100 mg BD for 28 days
136
Doxycycline for neurosyphilis
200 mg BD for 28 days
137
Doxycycline for uncomplicated genital chlamydia/nongonococcal urethritis
100 mg BD 7/7
138
Doxycycline for PID
100 mg BD 14/7
139
Doxycycline for Lyme disease
200 mg in 1-2 divided doses for 21/7
140
Formoterol for chronic asthma
12 mcg BD
141
Formoterol for COPD
12 mcg BD max 48 mcg
142
Ergometrine for PPH due to uterine atony
250-500 mcg IM/slow IV
143
Erythromycin for infection
250-500 mg qds
6. 25 mg/kg Q6h
12. 5 mg/kg for severe
144
Erythromycin for Impetigo
250-500 mg qds 5-7/7
145
Erythromycin for cellulitis/erysipelas
500 mg qds 5-7/7
146
Erythromycin for mild diabetic foot infection
500 mg qds 7/7
147
Erythromycin for leg ulcer infection
500 mg qds 7/7
148
Erythromycin for community-acquired pneumonia
500 mg qds 5/7
149
Erythromycin for sore throat
250-500 mg qds 5/7
150
Erythromycin for early syphilis
500 mg qds 14/7
151
Erythromycin for uncomplicated genital chlamydia/non-gonococcal urethritis
500 mg bd 14/7
152
Erythromycin for chronic prostatitis
250-500 mg qds
| IV 6.25 mg/kg q6h (12.5 mg/kg for severe infection)
153
Erythromycin for rosacea
500 mg bd 6-12 weeks
154
Erythromycin for acne
500 mg bd
155
ethinylestradiol/levonorgestrel for menstrual symptoms
1 tablet for 21 days, 7 day interval
| if started after day 6 of cycle need protection
156
ethinylestradiol/levonorgestrel for contracpetion
1 tablet for 21 days, same time each day
| if started after day 6 of cycle need protection
157
ethinylestradiol/levonorgestrel for menstrual symptoms 28 days
1 tablet for 21 days 1 inactive tablet for 7 days
| if started after day 6 of cycle need protection
158
ethinylestradiol/levonorgestrel for contraceptions 28 days
1 tablet 21 days, 1 inactive tablet for 7 days
| if started after day 6 of cycle need protection
159
Felodipine for Angina prophylaxis
5 mg OD mane
| elderly 2.5 mg OD mane
160
Felodipine for hypertension
5-10 mg OD mane
| elderly 2.5-10 mg OD mane
161
Fluconazole for candidal balanitis
150 mg for 1 dose
162
Fluconazole for vaginal candidiasis
150 mg for 1 dose
163
Fluconazole for recurrent vulvovaginal candidiasis
150 mg every 72 hours for 3 doses then 150 mg once weekly for 6 months
164
Fluconazole for mucosal candiasis
50 mg OD for 7-14 days
165
Fluconazole for tinea, pityriasis versiculor, dermal candidiasis
50 mg OD for 2-4 weeks max 6 weeks
166
Fluconazole for invasive candida infections
400 mg on the first day then 200-400 mg OD
167
Flumazenil for reversal of benzodiazepines in clinical procedures
200 mcg over 15 seconds then 100 mcg every 1 minute
| usual dose 300 to 600 mcg max 1 mg
168
Fluoxetine for major depression
20 mg OD
increased after 3-4 weeks
max 60 mg OD
169
Fluoxetine for bulimia
60 mg (40 mg in elderly)
170
Fluoxetine for OCD
20 mg increased to 60 mg (40 in elderly)
171
Fluticasone for asthma prophylaxis
100-500 mcg bd
172
Fluticasone for rhinitis
100 mcg OD
173
Folic Acid for Anemia
5 mg for 4 months
174
Folic acid for the prevention of NTDs
400 mcg daily before conception and till week 12
175
Folic acid for the prevention of NTD in high-risk women
5 mg before conception until 12 weeks
176
Folic acid for the prevention of methotrexate side effects
5 mg once weekly
177
Furosemide for oedema
40 mg daily mane then 20-40 mg OD
| IV/IM 20-50 mg then increased in steps of 20 mg every 2 hours
178
Furosemide for resistent oedema
80-120 mg
| IM/IV 20-50 mg increased in steps of 20 mg every 2 hours as needed
179
Furosemide for resistent hypoertension
40-80 mg
| IV/IM 20-50 mg then increased in steps of 20 mg as needed
180
Gabapentin for seizures
300 mg OD on day 1
300 mg BD on day 2
300 mg tds on day 3
then increase in steps of 300 every 2-3 days in 3 divided doses
usual dose 0.9-3.6g
181
Gabapentin for peripheral neuropathy
```
300 mg OD on day 1
300 mg BD on day 2
300 mg tds on day 3
then increase in steps of 300 every 2-3 days in 3 divided doses
max 3.6g
```
182
Gentamicin for a diabetic foot infection
5-7 mg/kg IV adjusted to serum concentration
183
Gentamicin for leg ulcer infection
5-7 mg/kg IV to serum concentration
184
Gentamicin for bacterial endocarditis or HACEK endocarditis
IM/IV 1 mg/kg Q12h over at least 3 minutes
185
Gentamicin for other infections
IV/IM 3-5 mg/kg in 3 divided doses Q8h IV over at least 3minutes
IV 5-7 mg/kg then adjusted to serum concentration
186
Gentamicin for surgical prophylaxis
1.5 mg/kg IV over 3 minutes 30 minutes before Q8 hourly
187
Gentamicin for pyelonephritis/catheter-associated UTI
5-7 mg/kg OD then adjusted to serum concentration
188
Glipizide for type 2 diabetes mellitus
2.5-5mg adjusted to response
| Max 20 mg per day
189
GTN for angina prophylaxis
sublingual 400-800 mcg
190
GTN for treatment of angina
400-800 mcg Q5min
191
GTN for unstable angina
IV 10-200 mcg/min max 400 to response
192
Haloperidol for nausea and vomiting treatment
1-2 mg
| elderly 500 mcg
193
Haloperidol for schizophrenia
2-10 mg daily in 1-2 divided doses
usual dose 2-4 mg daily in 1st episode
up to 10 mg in multiple-episode
(half the lowest adult dose for elderly, max 5 mg)
194
Haloperidol for acute delirium
1-10 mg in 1-3 divided doses, start at lowest
max 10 mg
elderly half the lowest adult dose, max 5 mg
IM 1-10 mg (500 mcg for elderly)
195
Haloperidol for manic episodes
2-10 mg in 1-2 divided doses
| elderly half the lowest adult dose max 5 mg
196
Haloperidol for psychomotor agitation
5-10 mg Q12h max 20 mg
elderly 2.5 mg Q12h max 5 mg
IM 5 mg Q1h max 15 mg
elderly 2.5mg Max 5 mg
197
Enoxaparin for VTE prophylaxis in moderate-risk surgical patients
SC 20 mg 2 hours before surgery
| 20 mg every 24 hours
198
Enoxaparin for VTE prophylaxis in high-risk surgical patients
Sc 40 mg 12 hours before surgery
| 40 mg every 24 hours
199
Enoxaparin for prophylaxis of DVT in medical patients
40 mg every 24 hours SC
200
Enoxaparin for treatment of DVT/PE in low risk of recurrence
1.5 mg/kg every 24 hours
201
Enoxaparin for Treatment of DVT/PE in patients at risk of recurrence
SC 1 mg/kg every 12 hours
202
Unfractionated Heparin for treatment of PE, unstable angina, and acute peripheral artery occlusion
5000 units loading dose (75 U/kg)
| then 18 units/kg/h
203
Unfractionated Heparin for treatment of severe PE
A loading dose of 10 000 units, then 18 units/kg/h
204
Unfractionated Heparin for treatment of DVT
IV loading dose 5000 units (75 U/kg) then 18 units/kg/h
205
Unfractionated Heparin for thromboprophylaxis in medical patients
SC 5000 units Q8-12h
206
Unfractionated Heparin for thromboprophylaxis in surgical patients
SC 5000 units 1 dose 2 hours before surgery then 5000 units every 8-12 hours
207
Hydrocortisone for thyrotoxic crisis
IV 100 mg Q6h
208
Hydrocortisone for acute hypersensitivity
IV 100-300 mg
209
Hydroxocobalamin for prophylaxis of macrocytic anaemia
IM 1 mg every 2-3 months
210
Hydroxocobalamin for pernicious anemia without neurological involvement
IM 1 mg three times a week for 2 weeks then 1 mg every 2-3 months
211
Hydroxocobalamin for pernicious anemia with neurological involvement
IM 1 mg once daily on alternate days till no further improvement
then
1 mg every 2 months
212
Immediate release Ibuprofen for pain
300-400 mg 3-4x increased to 600 mg 4x
| 200-400 mg tds
213
Modified released ibuprofen for pain
1.6 g once daily increased to 2.4 g in 2 divided doses
214
Immediate release ibuprofen for acute migraine
400-600 mg 1 dose
215
Ipratropium for reversible airway obstruction
20-40 mcg 3-4x
216
Ipratropium for COPD
20-40 mcg 3-4x
217
Ipratropium for acute bronchospasm
Nebulised
| 500 mcg
218
Ipratropium for life threatening/severe acute asthma
500 mcg Q4-6h
219
Isosorbide dinitrate for angina treatment and prophylaxis
30-120 mg in divided doses
| IV 1-10 mg/hour
220
Isosorbide dinitrate for LV failure
40-160 mg in divided doses max 240 mg
| IV 2-10 mg/h
221
Lactulose for constipation
15 mL bd
then
according to response
222
Lactulose for hepatic encephalopathy
30-50 mL tds adjusted
223
Levodopa for Parkinsons disease
84 mg inhaled PRN max 5x
224
Lignocaine/Lidocaine for infiltration anesthesia
max 200 mg
| max 500 mg with adrenaline
225
Lorazepam for anxiety
1-4 mg in divided doses
| 0.5-2 mg in elderly
226
Lorazepam for insomnia
1-2 mg nocte
227
Lorazepam for acute panic attack
IM/IV 25-30 mcg/kg Q6
| usual dose 1.5-2.5 mg Q6h
228
Lorazepam for Seizures
4 mg one dose, then 4mg after 10 minutes
229
Losartan for diabetic nephropathy
50 mg OD then 100 mg OD if needed
| >76 25 mg OD then 100 mg if needed
230
Losartan for chronic heart failure
12.5 mg OD increased at weekly interval to 150 mg OD
231
Losartan for hypertension
```
50 mg OD
then 100 mg if needed
>76 yo
25 mg OD
to 100 mg OD if needed
```
232
Magnesium sulfate for severe acute asthma/respiratory deterioration in anaphylaxis
1.2-2g over 20 minutes
233
Magnesium sulfate for prevention of seizures in pre-eclampsia
4g over 5-15 minutes
then
1g/h for 24 hours
234
Magnesium sulfate for the treatment of seizures and prevention of recurrence in pre-eclampsia
4g over 5-15 minute then 1g/h for 24 hours after seizure or delivery
235
Magnesium sulfate for hypomagnesemia
up to 40g over 5 days
maintenance 2.5-5 g daily
usually 3g
236
Magnesium sulfate for emergency treatment of arrhythmias
2g over 10-15 minutes
237
Metformin for T2DM
500 mg OD for 1 week
then 500 mg bd for 1 week
then 500 mg tds
max 2g per day
238
Metformin for PCOS
500 mg OD for 1 week
then 500 mg BD for 1 week
then 1.5-1.7g in 2-3 divided doses
239
Metoclopramide for nausea and vomiting
up to 500 mcg/kg daily in s divided doses
| weight > 60kg 10 mg up to tds
240
Metoclopramide for acute migraine
IV/IM 10 mg for 1 dose
241
Metoprolol for hypertension
immediate release: 100 mg OD then 200 mg in divided doses max 400 mg
MR 200 mg OD
242
Metoprolol for angina
Immediate release 50-100 mg 2-3x
| MR 200-400 mg
243
Metoprolol for arrhythmias
immediate release 50 mg 2-3 times up to 300 mg in divided doses
IV 5 mg at 1-2 mg/minute then 5 mg after 5 minutes
244
Metoprolol for migraine prophylaxis
Immediate release 100-200 mg in divided doses
| MR 200 mg
245
Metoprolol for hyperthyroidism
Immediate release 50 mg qds
246
Metronidazole for Anaerobic infection
400 mg Q8h 7/7
| IV 500 mg Q8h 7/7 over 20 minutes
247
Metronidazole for surgical prophylaxis
400-500 mg 2 hours before surgery then 400-500 mg Q8h for 3 doses
IV 500 mg 30 minutes before the procedure,
IV 500 mg Q8h for 3 doses
248
Misoprostol for termination of pregnancy following mifepristone
400 mcg to 800 mcg
249
Morphine for Acute pain
10 mg Q4h
elderly 5mg Q4h
slow infusion 5 mg Q4h
250
Morphine for chronic pain
5-10 mg Q4h
251
Morphine for MI
5-10 mg then 5-10 mg if needed at 1-2mg/min
| elderly 2.5-5 mg followed by 2.5-5mg if needed at 1-2 mg/min
252
Morphine for acute pulmonary edema
5-10 mg at 2 mg/minute
| elderly 2.5-5 mg at 2 mg/min
253
N-acetylcysteine for paracetamol OD
>40 kg 150 mg/kg over 1 hour in 200 mL glucose
then 50 mg/kg over 4 hours in 500 mL glucose
then 100 mg/kg over 16 hours in 1L glucose
254
Naloxone for opiod OD
IV 400 mg the 800 mg for 2 doses at 1 minute intervals
then 2 mg for 1 dose if no response
IM 400 mcg Q2-3 minutes
255
Nifedipine for Raynaud's syndrome
5 mg tds then adjust to response to 20 mg tds
256
Nifedipine for postponement of premature labor
20 mg then 10-20 mg 3-4x
257
Norethisterone for menorrhagia to arrest bleeding
5 mg tds 10/7
258
Norethisterone for menorrhagia to prevent bleeding
5 mg bd from day 19 to day 26
259
Norethisterone for dysmenorrhoea
5 mg tds for 3-4 cycles from day 5-24 of cycle
260
Norethisterone for contraception
350 mcg OD at the same time continuously (delayed by 3 hours if a missed pill)
261
Nortriptyline for depressive illness
75-100 mg in divided doses
max 150 mg
elderly 30-50 mg
262
Nortriptyline or neuropathic pain
10 mg OD nocte
| up to 75 mg
263
omeprazole for H.pylori eradication
20-40 mg bd 7/7
264
Omeprazole for gastric ulceration
20 mg OD 8 weeks
265
Omeprazole for duodenal ulceration
20 mg OD for 4 weeks
266
Omeprazole for prevention of gastric ulcer relapse
20 mg OD
267
Omeprazole for prevention of relapse of duodenal ulcer
20 mg OD
268
Omeprazole for NSAID associated ulcer
20 mg OD 4 weeks
269
Omeprazole for prophylaxis in patients with a history of NSAID associated ulcer
20 mg OD
270
Omeprazole for GORD
20 mg OD for 4-8 weeks
271
Omeprazole for severe oesophagitis
40 mg OD for 8 weeks
272
Omeprazole for acid reflux
10 mg OD
273
Ondansetron for prevention of postoperative nausea and vomiting
16 mg 1 hour before anesthesia
274
Ondansetron for treatment of postoperative nausea and vomiting
4 mg 1 dose IM/IV
275
Oxycodone for severe pain
Immediate release
5 mg
Q4-6h
Max 400 mg/day
Modified release
10 mg
Q12h
max 200 mg/12 h
Slow IV
1-10 mg
Q4h
IV 2 mg/h
SC 5 mg Q4h
276
Oxytocin for Induction of labor
IV 0.001-0.004 units/minuteincreased at 30 minute intervals until 3-4 contractions every 10 minutes
277
Oxytocin for prevention for PPH
Slow IV 5 units
| IM 10 units
278
Oxytocin for treatment of PPH
5 units
279
Paracetamol for pain/pyrexia
0.5-1g Q4-6h max 4g
280
Paracetamol for acute migraine
1g for 1 dose
281
Pethidine for acute pain
50-150 mg Q4h
282
Pethidine for obstetric analgesia
SC/IM 50-100 mg then 50-100 mg Q1-3h max 400 mg per day
283
Pethidine for postoperative pain
SC/IM 25-100 mg Q2-3 h
| elderly 25 mg Q2-3h
284
Phenytoin for seizures
3-4mg/kg daily or 150-300 mg OD
| 200-500 mg OD
285
Phenytoin for status epilepticus
loading dose 20 mg/kg then 100 mg Q6-8 hours
286
Prednisone for acute exacerbation of COPD
30 mg OD 7-14 days
287
Prednisone for croup
Children
| 1-2 mg/kg
288
Prednisone for asthma
40-50 mg OD 5/7
289
Prochlorperazine for psychosis/mania
12.5 mg bd 7/7 adjusted at 4-7 day intervals
usual dose 75-100 mg daily
IM 12.5-25 mg 2-3x
290
Prochlorperazine for anxiety
15-20 mg in divided doses, max 40 mg
291
Prochlorperazine for severe nausea and vomiting
20 mg then 10 mg after 2 hours
| IM 12.5 mg
292
Prochlorperazine for nausea and vomiting prevention
5-10 mg 2-3x
| IM 12.5 mg PRN
293
Prochlorperazine for labyrinthine disorders
5 mg tds increased to 30 mg in divided doses then reduced to 5-10 mg
294
Prochlorperazine for acute migraine
10 mg 1 dose
295
Pyridoxine for B6 deficiency
20-50 mg 1-3x
296
Pyridoxine for prophylaxis against isoniazid induced neuropathy
10-20 mg
297
Pyridoxine for treatment of isoniazid induced neuropathy
50 mg tds
298
Ranitidine for gastric/duodenal ulceration
150 mg bd for 4-8 weeks
| 300 mg OD 4-8 weeks nocte
299
Ranitidine for dyspepsia
150 mg BD 6 weeks
| 300 mg OD 6 weeks nocte
300
Ranitidine for NSAID induced gastric ulceration
150 mg bd for 8 weeks
| 300 mg OD 8 weeks nocte
301
Ranitidine for NSAID induced duodenal ulceration
300 mg bd for 4 weeks
302
Ranitidine for Prophylaxis against NSAID induced ulcers
300 mg bd
303
Ranitidine for GORD
150 mg BD for 8 weeks
| 300 mg OD for 8 weeks nocte
304
Ranitidine for moderate to severe GORD
600 mg daily in 2-4 divided doses 12 weeks
305
Risperidone for psychosis
IM 37.5 mg every 2 weeks adjusted in steps of 12 mg at intervals of at least 4 weeks
306
Risperidone for acute and chronic psychosis
2 mg in 1-2 divided doses for 1 day
then 4 mg in 1-2 divided doses for day 2
usual dose 4-6 mg
elderly initially 500 mcg BD increase in steps of 500 mcg to 1-2 mg bd
307
Risperidone for mania
2 mg od
increased in steps of 1 mg
usual dose 1-6 mg
elderly 500 mcg
increased in steps of 500 mcg bd to 1-2 mg bd
308
Salbutamol for Asthma
```
Immediate release 4 mg 3-4x, elderly 2 mg 3-4x
SC/IM 500 mcg Q4h
slow IV 250 mcg
IV 5 mcg/minute usual dose 3-10 mcg/min
inhaled 100-200 mcg up to 4 times
nebulised 200 mcg
```
309
Salbutamol for severe acute asthma
nebulized 5 mg every 20-30 minutes
310
Senna for constipation
7.5-15 mg daily
311
Simvastatin for hypercholesterolemia
10-20 mg OD
312
Simvastatin for familial hypercholesterolemia
40 mg then adjust at intervals of 4 weeks to 80 mg
313
Simvastatin for prevention of CVS events
20-40 mg
314
Sodium valproate for epilepsy
initially 600 mg in 1-2 divided doses
increased in steps of 150-300 mg every 3 days
maintenance 1-2g daily
315
Sodium valproate for migraine prophylaxis
200 mg bd then
| 1.2g-1.5g in divided doses if needed
316
Spironolactone for edema
100-400 mg daily
317
Spironolactone for congestive heart failure
25-200 mg daily
318
Spironolactone for moderate to severe heart failure
25 mg OD then adjust to response to 50 mg OD
319
Spironolactone for resistant hypertension
25 mg OD
320
Streptokinase for acute MI
1500 000 units within 12 hours of symptom onset over 60 minutes
321
Streptokinase for DVT
250 000 units over 30 minutes the 100 000 units every 1 hour for 72 hours
322
Streptokinase for PE
250 000 units over 30 minutes then 100 000 units every 1 hour for 24 hours
323
Co-trimoxazole for infection
960 mg bd
| IV 960 mg Q12 increased to 1.44 g if needed
324
Cotrimoxazole for a diabetic foot infection
960 mg bd
IV 960 mg Q12h
increased to 1.44g if needed
325
Cotrimoxazole for Leg ulcer infection
960 mg BD 7/7
| IV 960 mg Q12 increased to 1.44g if needed
326
Cotrimoxazole for hospital-acquired pneumonia
960 mg BD for 5/7
327
Cotrimoxazole for acute exacerbation of COPD
960 mg BD 5/7
IV 960 mg Q12h
increased to 1.44g if needed
328
Sumatriptan for acute migraine
50-100 mg then 50-100 mg after at least 2 hours
329
Sumatriptan for acute cluster headache
SC 6 mg for 1 dose then 6 mg after at least 1 hour
330
Temazepam for Insomnia
10-20 mg OD or 30-40 mg OD
| elderly 10 mg OD or 20 mg OD
331
Tenofovir for HBV
25 mg OD
332
Tenofovir disoproxil for HIV
245 mg OD
333
Thiamine for mild B1 deficiency
25-100 mg
334
Thiamine for severe B1 deficinecy
200-300 mg in divided doses
335
Alteplase for acute MI
```
10 mg within 6-12 hours of sx onset
then
IV 50 mg over 60 minutes
then
10 mg for 4 infusions, over 30 minutes each
```
336
Alteplase for PE
10 mg over 1-2 minutes then 90 mg over 2 hours
337
Alteplase for acute ischamic stroke
900 mcg/kg within 4.5 hours of symptom onset over 60 minutes
338
Tramadol for moderate to severe pain
IM/IV/SC 50-100 mg Q4-6h
max 400 mg/day
Immediated release PO 100 mg then 50-100 mg Q4-6h Max 400 mg/day
339
Tramadol for moderate to severe chronic pain
Immediate release 50 mg
| Max 400 mg/day
340
Tranexamic acid for menorrhagia
1g tds for up to 4 days starting when menstruation starts mac 4g per day
341
Tranexamic acid for epistaxis
1g tds 7/7
342
Vancomycin for c.difficile infection
125 mg Q6h for 10/7
| increased to 500 mg if needed
343
Vancomycin for a diabetic foot infection
IV 15-20 mg/kg Q8-12h
344
Vancomycin for cellulitis/erysipelas
IV 15-20 mg/kg Q8-12h
345
Vancomycin for infection
15-20 mg/kg Q8-12h
346
Vancomycin for surgical MRSA prophylaxis
1g 1 dose
347
Vitamin K1 (phytomenadione) for Major bleeding in patients on warfarin
5 mg 1 dose
348
Warfarin prophylaxis in rheumatic heart disease, AF, prosthetic valve, VTE, TIA
5-10 mg on day 1
maintemce 3-9 mg
same time each day
349
Zopiclone for insomnia
7.5 mg OD for up to 4 weeks
| elderly 3.75 mg OD up to 4 weeks
350
Daily Fluid requirements
25-30 mL/kg/day
351
Daily Na, K, Cl requirements
1 mmol/kg/day
352
Daily glucose requirement
50-100g/day
353
Resuscitation fluids
500 mL bolus of NaCl or Hartmann's over less than 15 minutes
reassess, if ongoing hypovolemia further 250-500 mL bolus
Repeat to max 2000 mL
