Mcb 1 Flashcards

(17 cards)

1
Q

What is the Gram stain classification of Acinetobacter?

A

Gram negative

Acinetobacter is classified as Gram negative, indicating its cell wall structure.

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2
Q

What is the shape of Acinetobacter bacteria?

A

Coccobacilli

Coccobacilli are short, oval-shaped bacteria.

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3
Q

Is Acinetobacter motile or non-motile?

A

Non-motile

Acinetobacter does not have flagella and cannot move independently.

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4
Q

What type of aerobe is Acinetobacter?

A

Strict aerobe

Acinetobacter requires oxygen for growth.

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5
Q

What are the two most common species of Acinetobacter found in clinical specimens?

A

A. baumannii, A. iwofii

These species are frequently isolated in clinical settings.

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6
Q

What percentage of all nosocomial infections do Acinetobacter species account for?

A

1-3%

This indicates Acinetobacter’s role as an opportunistic pathogen in hospitals.

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7
Q

What are some environmental reservoirs for Acinetobacter?

A
  • Soil
  • Fresh water
  • Vegetables
  • Animals
  • Body of lice, fleas, ticks

Acinetobacter can be found in various natural and environmental settings.

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8
Q

What is a common site of colonization for Acinetobacter in healthy adults?

A

Pharynx

Approximately 25% of healthy adults may carry Acinetobacter in their pharynx.

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9
Q

What is a major virulence factor of Acinetobacter?

A

Polysaccharide capsule

The capsule helps prevent complement activation and delays phagocytosis.

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10
Q

What are some diseases associated with A. baumannii?

A
  • UTI
  • Pneumonia
  • Tracheobronchitis
  • Endocarditis
  • Meningitides
  • Septicemia
  • Burn infections
  • Eye infections

A. baumannii is linked to various opportunistic infections.

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11
Q

What type of diagnostic test is used to identify Acinetobacter?

A

Culture

Culturing the bacteria is essential for identification and testing antibiotic susceptibility.

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12
Q

What selective media can be used to isolate Acinetobacter?

A
  • CHROME Agar
  • Leeds Acinetobacter Agar

These media help select for Acinetobacter during culture.

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13
Q

What is the result of a Gram stain for Acinetobacter?

A

Tiny diplococci, Gram negative

Acinetobacter appears as small, paired cocci under the microscope.

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14
Q

What antibiotics are commonly used to treat Acinetobacter infections?

A
  • Carbapenem (Imipenem, Meropenem)
  • Polymyxin
  • Tigecycline
  • Aminoglycosides

These classes of antibiotics are often effective against Acinetobacter.

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15
Q

What is a major problem associated with Acinetobacter treatment?

A

Antibiotic resistance

Many strains of Acinetobacter, particularly A. baumannii, have developed multidrug resistance (MDR).

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16
Q

What is one method for preventing Acinetobacter infections?

A

Hand washing

Proper hygiene practices are essential in controlling the spread of Acinetobacter.

17
Q

Fill in the blank: Acinetobacter is known to form _______ for surface colonization.

A

biofilms

Biofilm formation aids in persistence and resistance against host defenses.