MCBG 10 - collagen Flashcards Preview

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Flashcards in MCBG 10 - collagen Deck (12):
1

Name the two ways proteins are delivered to the plasma membrane for export?

regulated
constitutive pathway

2

Whats the most abundant protein in the body?

Collagen. 25-35% whole protein content

3

Whats the basic unit of collagen?

Tropocollagen

4

What is the structure of a collagen fibre?

3 triple helix structure

5

Why are glycine's found in collagen?

It is the only amino acid with a small enough side chain in the middle of the helix

6

How often is glycine found in a collagen molecules?

Every third Amino Acid

7

What bond stabilised collagen?

H bonds

8

Where is type one collagen found?

(2 alpha-1 chains and 1 alpha-2)
Skin, tendons, ligaments, bone. (90% of collagen)

9

Where is type 2 collagen found?

Cartilage, Intervertebral discs

10

Where is type 3 collagen found?

reticulate (component of reticular fibres)

11

Where is Type IV found?

forms basal lamina, the epithelium-secreted layer of the basement membrane.

12

Where is Type V found?

cell surfaces, hair and placenta