MCQs Flashcards
(33 cards)
What is a double positive Thymocyte?
- CD2-CD3+CD4-CD8+
- CD2+CD3-CD4+CD8-
- CD2-CD3+CD4+CD8-
- CD2+CD3+CD4+CD8+
- CD2+CD3+CD4+CD8+
Which of the following characteristics are not used to classify the lymphatic newformations?
- Specific cancerogens exposure
- Origin of the tumor cells
- Morphology + cytology of tumor cells
- Genetranslocations
Specific cancerogens exposure
Which of the white blood cells is capable of future differentiation in tissue?
- Neutrophil
- Monocyte
- Eosinophil
- Basophil
- Monocyte
White blood cells are traditionally grouped into three major categories—granulocytes, monocytes, and lymphocytes—on the basis of their appearance in the light microscope.
Front dispersion of the light/FSC in fluoroscent cytometry is an indicator for
- Count of cells
- Form of cells
- Density of cells
- Granulation of cells
- Density of cells
22 year-old woman with erithematous rash including her cheeks and nose and it appears everytime
she spends a few minutes out in a sunny day. On physical examination between these episodes,
there was nothing found. There is normal kidney function. On immunofluorescent biopsy of the skin
that takes part in the rash formation, it shows the IgG along the basal membrane. There is no IgG on
the not in the rash included skin. Test for ANA is negative. Which of these diseases ist he proper
diagnosis?
- Restricted systemic sklerosis
- Systemic lupus erythematosus
- Discoid lupus erythematosus
- Atopic dermatitis
- Systemic lupus erythematosus
Which of the following is a proof for medication induced lupus?
- Anti SS A Antibodies
- Anti smith antibodies
- Anti histone antibodies
- Rheuma factor
- Anti histone antibodies
Homogenous type of light in indirect immunofluorency would give which of these antibodies?
- Anti smith antibodies
- Anti histone antibodies
- Anti SS A antibodies
- Anti RNP antibodies
- Anti histone antibodies
Which of the fllowing markers would be expressed on the population of T-Cytotoxic cells?
- Only CD4
- CD3 and CD8
- CD19 and CD20
- CD3 and CD4
- CD3 and CD8
The analysis of the types of T-Cells with fluorcytometry would be most usefull when diagnosing which disease? - Severe IgA deficiency - Severe combined immunodefficiency - Brutons disease - Multiple myeloma
- Severe combined immunodefficiency
How many anitgen presenting places does a typical IgM molecule have?
- 2
- 4
- 6
- 10
- 10
The skin, the secretion of lactic acid, bile and stomach acid, movement of the cilia in the respiratory tract are presenting which type of immunity?
- Innate
- Autoimmune
- Specific
- Accquired
- Innate
INNATE IMMUNITY. Innate, or nonspecific, immunity is the defense system with which you were born. It protects you against all antigens. Innate immunity involves barriers that keep harmful materials from entering your body. These barriers form the first line of defense in the immune response.
A human recovering from a bacterial infection. After testing his serum, antibodies where found
against the protein which is usually found in the cytoplasm of the with the infection associated
bacteria. Which of the following is correct?
- MHC molecues Class I have presented the bacterial antigen to CD5+ T-Cells
- MHC molecules Class II have presented the bacterial antigen to CD4+ T-Cells
- B cells have recognized the bacterial antigen without the help of the T-Cellss
- MHC molecules Class I have presented bacterial antigen to CD4+ T-Cells
- MHC molecules Class II have presented the bacterial antigen to CD4+ T-Cells
Which of the following would be examined in a patient with myeloperoxidase deficiency?
- Incapability of forming IgG
- Functioning defect of NK-Cells
- Functioning defect of T-Cells
- Functioning defect of Neutrophils
- Functioning defect of Neutrophils
Which of the following is the power of attraction between antibody and antigen ?
- Affinity
- Covalence
- Van deer Waals forces
- Avidity
- Affinity
During lowered amount of interleucin-4, we have
- Low amount of IgE
- Low amount of eosinophils
- Higher risk of tumor formation
- Incapability of fighting the viral infections
- Low amount of IgE
B cells produce IgG1 and IgE when stimulated with anti-CD40 and IL-4.
The graft-verus-host-disease (GVHD) after transplantation of stem cells is mediated by which of the following? - NK-Cellsa - Neutrophills - Mature T-Cells - Mature B-Cells
- Mature T-Cells
Graft-vs-host disease (GVHD) is caused by a donor T cell anti-host reaction that evolves over several weeks to months, suggesting a requirement for persistent alloreactive T cells.
The class of the immunoglobuline cells is defined by
- Heavy chains (H-chain)
- Light chains (L-chain)
- Disulfate connections
- Variable area (V-region)
- Heavy chains (H-chain)
The five primary classes of immunoglobulins are IgG, IgM, IgA, IgD and IgE. These are distinguished by the type of heavy chain found in the molecule.
Antigen receptors of T-lymphocytes bind to HLA molecules Class II with the help of which additional molecule? - CD3 - CD8 - CD4 - CD2
- CD4
Contact dermatitis can be characterized by all of the following EXCEPT
- Cells of Langerhans, acting like antigen presenting cells
- Generation of sensibilized T-Cells
- Forming of antigen-antibody-complex
- Formation of a complex of hapten and own body antigen
- Forming of antigen-antibody-complex
All of the below characteristics are specific for the components of the complement, EXCEPT
- Thermolability
- Normally found in plasma
- Mainly synthesized in liver
- Are identical with fibrinogen
- Are identical with fibrinogen
Syndrome of DiGeorge can be characterized by all oft he following, EXCEPT
- Decreased amount of mature T-Cells
- Normal amount of neutrophilic granulocytes
- Cardiac anormalities
- Hypoplasia of parathyroid cells
- Normal amount of neutrophilic granulocytes
The classic pathway of the complement system is activated by
- Most viruses
- Antigen-antibody-complex
- Fungal cell wall
- All oft he above
- Antigen-antibody-complex
in alternative pathway it is activated by bacterial endotoxin
in lectin pathway it is activated by mannose binding lectin
42 year old men has lost 7kg in the last 2 years. During that time, he has experieced pain and edema
around the small joints of hands and feet. This sounds like he has had a high amount of infections oft
he raspiratory tract with isolated staphylococcus aureus, streptococcus pneumoniae and
pseudomonas aeuroginosa. He has chronic diarrhea and cysts of giardia lamblia in feces. His ANA test
is negative. Quality examination of serum immunoglobulins finds hypogammaglobulinemia. With
fluorcytometry normal amount of T-Cells, slight lowering of B-Cells was found. Which ist he most
likely diagnosis?
- HIV infection
- Diabetes mellitus
- Humoral imunity deficiency
- Combined immune deficiency
- Humoral imunity deficiency
Which oft he following is the best for analysis of specific cytokines?
- Meassuring of hemotaxis of lymphocytes
- Blast formation
- T-Cells proliferation
- ELISA method
- ELISA method
The enzyme-linked immunosorbant assay (ELISA)
