MDS Flashcards

1
Q

treatment for <55 yo

A

Allogeneic BMT

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2
Q

treatment for > 55 yo

A

Azacitidine + supportive with blood transfusions

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3
Q

When to give EPO

A

when EPO is < 500

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4
Q

treatment for 5q gene deletion

A

Lenalidomide

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5
Q

clinical features

A

hyposegmented PMNs, macrocytosis, megakaryocytes, hyPERcellular marrow (unlike pancytopenia/aplastic anemia in which BM is hypOcellular). May transform to AML (survival is <1 yr).

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