Mecanosensibles Flashcards

(6 cards)

1
Q

TRPV1

A

Dolor/ temperatura

Activación:
- transduction de señales nocioceptivas
~ potenciados por ph< 5.9
~ citokinas proinflamatorias

Temperaturas altas: >42C

Modulación:

  • Vm
  • ATP
  • kinases
  • Ca
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2
Q

TRPV

A

TERMORECEPTORES

TRPV2: > 52C - hipotonicidad
TRPV3: > 34-38C
TRPV4: > 27-34C - hipotonicidad

SELECTIVOS

TRPV5 y TRPV6 : canales cationicos activados por calcio

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3
Q

TRPM

A

8 canales

FRÍO

TRPM4 y 5: cationes monovalentes
- regulados por Ca

TRPM5: temperatura > 15-35C
-órganos internos

TRMP6 y 7: cationes divalentes

TRMP8: termoreceptor >23-28C

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4
Q

TRPA1

A

TERMORECEPTORES

  • <18C
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5
Q

TRPP

A

Aumento del Ca intracelular

Mecanosensibles

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6
Q

TRPML

A

Canales para cationes divalentes

Mucolipina

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