Mechanism of Action Flashcards
(23 cards)
1
Q
ADRENALINE
A
- A NATURALLY OCCURING SYMPATHOMIMETIC AGENT
- CAUSES PERIPHERAL VASOCONSTRICTION
- STIMULATION OF CARDIAC CONDUCTION SYSTEM CAUSES INCREASED CONTRACTIONS
- CAUSES BRONCHODILATION AND DILATION OF BLOOD VESSELS IN MUSCLES
2
Q
AMIODARONE
A
- A CLASS III ANTI-DYSRHYTHMIC AGENT THAT PROLONGS ACTION POTENTIAL DURATION AND REFRACTORY PERIOD OF ATRIAL, NODAL AND VENTRICULAR TISSUE
3
Q
ASPIRIN
A
- ANALGESIC
- ANTIPYRETIC
- ANTI-INFLAMMATORY
- ANTI-PLATELET AGGREGATION AGENT
- MINIMISES PLATELET AGGREGATION AND THROMBUS FORMATION TO RETARD PROGRESSION OF CORONARY ARTERY THROMBUS
4
Q
ATROPINE
A
- ANTI-CHOLINERGIC AGENT THAT INHIBITS THE ACTION OF ACETYLCHOLINE ON POST GANGLIONIC NERVES AT THE NEUROEFFECTOR SITE
- BLOCKS VAGAL STIMULATION TO ALLOW SYMPATHETIC RESPONSE TO
- INCREASE HR
- INCREASE SA NODE FIRING RATE
- INCREASED CONDUCTION VELOCITY
THROUGH THE AV NODE - ANTIDOTE TO REVERSE EFFECTS OF CHOLINESTERASE INHIBITORS –> ORGANOPHOSPHATE POISONING
5
Q
COPHENYCAINE
A
- A TOPICAL ANAESTETIC AGENT AND HAEMORRHAGE CONTROL AGENT FOR RELIEF OF SURFACE PAIN, NASAL AND ORAL BLEEDING
6
Q
FENTANYL
A
- A SHORT ACTING SYNTHETIC NARCOTIC ANALGESIC
7
Q
GLUCAGON
A
- A HYPERGLYCAEMIC AGENT THAT CONVERTS STORED LIVER GLYCOGEN TO GLUCOSE TO INCREASE BLOOD GLUCOSE CONCENTRATION
8
Q
GLUCOSE 10%
A
- A HYPERTONIC CRYSTALLOID SOLUTION THAT PROVIDES A READILY AVAILABLE SOURCE OF ENERGY
9
Q
GLUCOSE ORAL GEL
A
- RAPIDLY ABSORBED FROM ORAL/BUCCAL MUCOSA TO INCREASE BLOOD GLUCOSE CONCENTRATION
10
Q
GTN
A
- NITRATE THAT CAUSES THE RELAXATION OF VASCULAR SMOOTH MUSCLE RESULTING IN:
- VASODILATION
- PERIPHERAL POOLING
- REDUCED LV AND DIASTOLIC PRESSURE
(PRELOAD)
- REDUCED SYSTEMIC VASC. RESISTANCE
(AFTERLOAD)
- REDUCED MYOCARDIAL ENERGY AND
OXYGEN REQUIREMENTS
- RELAXES SPASM OF CORONARY ARTERIES
11
Q
HEPARIN
A
- NATURALLY OCCURING ANTICOAGULANT WHICH INHIBITS THE CLOTTING OF BLOOD BY ENHANCING THE RATE AT WHICH ANTITHROMBIN III NEUTRALISES THROMBIN AND ACTIVATED FACTOR X (Xa)
12
Q
NORMAL SALINE
A
- A STERILE ISOTONIC CRYSTALLOID SOLUTION
13
Q
IPRATROPIUM
A
- AN ANTICHOLINERGIC BRONCHODILATOR
- INHIBITS THE VAGAL REFLEXES THAT MEDIATE BRONCHOSPASM
14
Q
KETAMINE
A
- RAPID ACTING DISSOCIATIVE ANAESTHETIC
15
Q
LIGNOCAINE
A
- SODIUM CHANNEL BLOCKER
- PREVENTS THE INITIATION AND PROPAGATION OF NERVE IMPULSES
16
Q
METHOXYFLURANE
A
- A HALOGENATED ETHER THAT PRODUCES POWERFUL MODIFICATION OF THE AWARENESS OF PAIN WITH AN ASSOCIATED LIGHT HEADED SENSATION
- HIGHLY LIPID SOLUBLE, ALLOWING FOR SLOW INDUCTION AND EMERGENCE
17
Q
MIDAZOLAM
A
- WATER-SOLUBLE BENZODIAZEPINE THAT HAS ANXIOLYTIC, SEDATIVE AND ANTICONVULSIVE CHARACTERISTICS.
- BONDS WITH RECEPTORS IN THE CNS TO INCREASE THE INHIBITORY EFFECTS OF GABA
- LIPID-SOLUBLE IN PHYSIOLOGICAL pH AND REACHES THE CNS QUICKLY
18
Q
NALOXONE
A
- A PURE OPIOID ANTAGONIST THAT EXERTS ITS EFFECT BY COMPETITIVE INHIBITION AT OPIOID RECEPTOR SITES
- IT PREVENTS/REVERSES THE EFFECTS OF OPIOIDS INCLUDING:
- RESPIRATORY DEPRESSION
- SEDATION
- HYPOTENSION - IN THE ABSENCE OF OPIOIDS IT EXHIBITS NO PHARMACOLOGICAL ACTIVITY
19
Q
ONDANSETRON
A
- ANTI-NAUSEANT/ANTI-EMETIC
- SELECTIVE 5-HT3 RECEPTOR ANTAGONIST BLOCKING SEROTONIN CENTRALLY IN THE CHEMORECEPTOR TRIGGER ZONE AND PERIPHERALLY ON VAGUS NERVE TERMINALS
20
Q
OXYGEN
A
- TREATMENT FOR HYPOXAEMIA
- SHOWN TO HAVE NO EFFECT ON BREATHLESSNESS IN NON-HYPOXAEMIC PTS
21
Q
PARACETAMOL
A
- A P-AMINOPHENOL DERIVATIVE THAT EXHIBITS ANALGESIC AND ANTIPYRETIC ACTIVITY
22
Q
PREDNISOLONE
A
- A STERIOD THAT PREVENTS THE RELEASE OF INFLAMMATORY MEDIATORS
23
Q
SALBUTAMOL
A
- SHORT ACTING BETA-2 ADRENO-RECEPTOR STIMULANT
- CAUSES RELAXATION OF BRONCHIAL SMOOTH MUSCLE
SYMPATHOMIMETIC
