Mechanism of Hormone Action Lec I Flashcards
(6 cards)
For amino acid based hormones:
all non polar (lipid based) since all cell plasma membranes are phospholipid bilayers integrated w/ cholesterol molecules
Amino acid based hormones are defined as
polar molecules with positively and negatively charged ends
amino acid hormones must deliver their message from _____________
the outside by binding to receptors on the target cell surface
The first messengers for amino acid hormones are:
attaching to the receptors on target cell plasma membrane which acts as the 1st messengers, relays the original message from the endocrine gland to target cell surface
The second messenger for amino acid hormones are:
intracellular cyclic AMP which indirectly activates other enzymes in target cell; leads to functional changes in target cell activity
In steroid homones (cholesterol/lipid)