Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Drugs > Mechanisms Of Action > Flashcards

Mechanisms Of Action Flashcards

1
Q

Acetaminophen/APAP (MOA)

A

Inhibits cyclooxygenase to increase the pain threshold
Acts on the hypothalamus to reduce fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Acetylsalicylic acid/ASA (MOA)

A

Blocks formation of thromboxane A2 which prevents platelets from clumping (aggregating)
Prevents clots from forming

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Activated charcoal (MOA)

A

Binds (adsorbs) and inactivates toxic substances in the gastrointestinal tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Adenosine (MOA)

A

Slows atrioventricular conduction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Albuterol sulfate (MOA)

A

Relaxes bronchial smooth muscle resulting in bronchodialation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Amiodarone (MOA)

A

Blocks sodium, potassium, and calcium channels
Prolongs their action potential and repolarization
Slows the sinus rate
Increases the length of the PR interval and QT interval

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Atropine sulfate (MOA)

A

Blocks the action of acetylcholine
Increases the heart rate
Reverses the symptoms of cholinergic poisonings

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Bumetanide (MOA)

A

Inhibits the reabsorption of sodium and chloride in the kidneys
Increases the output of urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Calcium chloride (MOA)

A

Increases intercellular calcium levels
Increases myocardial contractility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Calcium gluconate 2.5% topical gel (MOA)

A

Combines with hydrofluoric acid to neutralize the fluoride ion, forming insoluble calcium fluoride
Stops the fluoride ion from penetrating into tissue and bone, preventing further damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Calcium gluconate (MOA)

A

Increases intracellular and extracellular calcium levels
Increases cardiac automaticity
Increases cardiac contractility
Stabilizes myocardial membranes in hyperkalemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Dexamethasone (MOA)

A

Suppresses acute and chronic inflammation
Produces immunosuppressive effect
Stabilizes cell membranes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Dextrose 50% (MOA)

A

Increases the glucose levels in the blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Diazepam (MOA)

A

Produces sedation by acting on the limbic system, the thalamus and hypothalamus
Binds to gamma-amino butyric acid (GABA) benzodiazepine receptors in the brain
Raises the seizure threshold
Produces tranquilizing (antianxiety) effect on the central nervous system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Diltiazem (MOA)

A

Slows extracellular calcium ion influx across myocardial cell membranes
Slows conduction through the sinoatrial node and the atrioventricular node
Slows ventricular conduction rates in atrial fibrillation and atrial flutter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Diphenhydramine (MOA)

A

Blocks H1 histamine receptors
Reverses a phenothiazine reaction with extrapyramidal symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Dopamine (MOA)

A

Increases the heart rate
Increases the force of myocardial contractility
Increases the blood pressure
Increases the preload

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

epinephrine (MOA)

A

Alpha-adrenergic response
-vasoconstriction

Beta1-adrenergic responses
-increases the heart rate
-increases myocardial contractility

Beta2-adrenergic response
-relaxes bronchial smooth muscle resulting in bronchodialation (one more scroll down)

Blocks histamine receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Etomidate (MOA)

A

Produces depression of the central nervous system
Produces anesthesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Fentanyl (MOA)

A

Alleviates pain by depressing the central nervous system
Depresses respiratory centers in the brainstem
Decreases venous return to the heart
Decreases preload
Decreases after load

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Furosemide (MOA)

A

Inhibits the reabsorption of sodium and chloride in the kidneys
Increases the output of urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Glucagon (MOA)

A

Increases the glucose levels in the blood by releasing glycogen store in the liver
Increases the force of myocardial contractility
Increases the heart rate

23
Q

Hydroxocoblamin (MOA)

A

Binds with cyanide to form cyanobalamin

24
Q

Ibuprofen (MOA)

A

Inhibits prostaglandin synthesis

25
Iprtropium bromide (MOA)
Blocks acetylcholine receptors on bronchial smooth muscle Dialates the larger airways resulting in bronchodilation
26
Ketamine (MOA)
Blocks pain receptors Produces dissociative state Produces anesthesia
27
Lidocaine (MOA)
Suppresses ventricular ectopic activity Increases the threshold of ventricular fibrillation
28
Lorazepam (MOA)
• Produces sedation by acting on the limbic system, the thalamus, and cortex • Binds to gamma-amino butyric acid (GABA) benzodiazepine receptors in the brain • Raises the seizure threshold • Produces tranquilizing (anti-anxiety) effect on the central nervous system
29
Magnesium sulfate (MOA)
• Decreases ventricular irritability • Decreases release of acetylcholine that inhibits muscular excitability • Causes uterine relaxation • Relaxes bronchial smooth muscle resulting in bronchodilation • Raises the seizure threshold in eclampsia and preeclampsia
30
Methylprednisolone (MOA)
• Suppresses acute and chronic inflammation • Produces immunosuppressive effect • Stabilizes cellular membranes
31
Midazolam (MOA)
• Produces sedation by acting on the limbic system, the thalamus, and the hypothalamus • Binds to gamma-amino butyric acid (GABA) benzodiazepine receptors in the brain • Raises the seizure threshold • Produces tranquilizing (anti-anxiety) effect on the central nervous system
32
Morphine sulfate (MOA)
• Alleviates pain by depressing the central nervous system • Depresses brainstem respiratory centers • Decreases venous return to the heart • Decreases preload • Decreases afterload
33
Naloxone (MOA)
• Acts as a competitive antagonist at opiate receptors in the central nervous system • Reverses the effects of narcotics and synthetic analgesic drugs º central nervous system depression º respiratory depression º respiratory arrest
34
Nitroglycerin (MOA)
• Relaxes vascular smooth muscle • Dilates coronary arteries resulting in increased blood flow to the myocardium • Decreases workload on the heart • Decreases myocardial oxygen demand • Decreases preload • Decreases afterload
35
Nitrous oxide 50% (MOA)
Alleviates pain by depressing the central nervous system
36
Norepinephrine
• Alpha-adrenergic response causing vasoconstriction • Beta-1 adrenergic response causing increased heart rate and increased myocardial contractility
37
Ondansetron (MOA)
• Blocks serotonin 5-HT3 receptor sites in the central nervous system • Inhibits nausea and vomiting
38
Oral glucose (MOA)
Increases the glucose levels in the blood
39
Oxygen (MOA)
• Reverses hypoxia • Increases oxygenation of tissues • Increases saturation of hemoglobin
40
Oxytocin (MOA)
• Binds to oxytocin receptor sites on the surface of uterine smooth muscles • Increases the force and frequency of uterine contractions
41
Phenylephrine nasal spray 0.5% (MOA)
• Stimulates alpha receptors to vasoconstriction blood vessels in the nasal mucosa • Reduces the risk of bleeding during insertion of a naso-tracheal tube
42
Pralidoxime chloride (2-Pam) (MOA)
Regenerates cholinesterase activity that became inhibited by an organophosphate pesticide
43
Proparacaine ophthalmic solution 0.5% (MOA)
Alleviates pain at the ophthalmic nerve cell membrane
44
Racemic epinephrine (MOA)
• Beta-2 adrenergic response • Relaxes bronchial smooth muscle resulting in bronchodilation
45
Rocuronium (MOA)
• Binds to nicotinic cholinergic receptor sites at the nerve fiber’s motor end plate • Antagonizes acetylcholine binding at the nerve fiber’s motor end plate resulting neuromuscular blockade
46
Sodium bicarbonate 7.5-8.4% (MOA)
• Buffers metabolic acidosis • Increases the pH of blood and urine
47
Succinylcholine (MOA)
Inhibits neuromuscular transmission resulting in temporary paralysis
48
Tetracaine (MOA)
Alleviates corneal pain
49
Thiamine (MOA)
Metabolizes carbohydrates
50
Vasopressin (MOA)
Produces vasoconstriction
51
Verapamil (MOA)
• Slows extracellular calcium ion reflux across myocardial cell membranes • Slows conduction through the sinoatrial node and the atrioventricular node • Slows the ventricular conduction rate in atrial fibrillation and atrial flutter
52
0.9% sodium chloride solution (MOA)
• Parenteral maintenance and replacement of extracellular fluid loss • Parenteral maintenance and replacement of extracellular electrolyte loss
53
Lactate Ringer’s solution (MOA)
• Parenteral maintenance and replacement of extracellular fluid loss • Parenteral maintenance and replacement of extracellular electrolyte loss
54
5% dextrose in water (MOA)
Parenteral maintenance and replacement of carbohydrate

Drugs (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions