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Flashcards in Mechanotransduction Deck (3)
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What is the ECM?

Network and reservoir of extra cellular and signalling molecules which are secreted locally to ensure cell and tissue cohesion


What are Focal Adhesions?

Integrin based cell matrix physical contacts that transducer and integrate mechanical and biochemical cues from the environment through the recruitment of intracellular multi protein assemblies connected to Actin cytoskeleton


What is Mechanosensing?

The ability of a cell to sense mechanical cues of its micro-environment, includes not only all components of force, stress and strain, but also substrate rigidity, topography and adhesiveness