Med List 8: Diabetes & Cholesterol

Question 1

Omega-3-fatty acids

Answer 1

Brand: Lovaza

Strength: 1 g

Frequency:
- 4g once daily
- 2g twice daily

Indications:
- hypertriglyceridemia
- dietary supplement

Tips:
- burping and taste disturbances
- shallow hole
- refrigerate to reduce taste/smell

Question 2

Fenofibrate

Answer 2

Brand: Trilipix, Tricor

Strength: 45, 48, 138, 145 mg

Frequency: daily

Indications:
- hypertriglyceridemia

Tips:
- increased liver enzymes
- discontinue if gallstones form
- photosensitivity

Question 3

Atorvastatin

Answer 3

Brand: Lipitor

Strength: 10, 20, 40, 80 mg

Frequency: daily

Indications:
- Hyperlipidemia: reduce LDL, reduce triglycerides, increase HDL
- Cardiovascular disease prevention

Tips:
- increased liver enzymes
- report unusual muscle pain, weakness, dark urine –> rhabdomyolysis
- avoid grapefruit juice
- contraindicated in pregnancy
- diarrhea

Question 4

Rosuvastatin

Answer 4

Brand: Crestor

Strength: 5, 10, 20, 40 mg

Frequency: daily

Indications:
- Hyperlipidemia: reduce LDL, reduce triglycerides, increase HDL
- Cardiovascular disease prevention

Tips:
- increased liver enzymes
- report unusual muscle pain, weakness, dark urine –> rhabdomyolysis
- avoid grapefruit juice
- contraindicated in pregnancy
- diarrhea

Question 5

Ezetimibe

Answer 5

Brand: Zetia

Strength: 10mg

Frequency: daily

Indications:
- hyperlipidemia

Tips:
- increased liver enzymes
- diarrhea

Question 6

Insulin Lispro (rapid acting)

Answer 6

Brand: Humalog

Strength: 100 units/ml

Frequency: inject 15 min before or immediately after meals

Indications:
- Type 1 and 2 Diabetes

Tips:
- low blood sugar (sweating, nausea, dizziness)
- refrigerate unopened vials
- discard after 28 days at room temp
- let syringe reach room temp before injection to avoid pain
- rotate injection sites

Question 7

Insulin glargine (long acting)

Answer 7

Brand: lantus

Strength: 100 units/ml

Frequency: once daily

Indications:
- Type 1 and 2 Diabetes

Tips:
- low blood sugar (sweating, nausea, dizziness)
- refrigerate unopened vials
- discard after 28 days at room temp
- let syringe reach room temp before injection to avoid pain
- rotate injection sites

Question 8

Metformin

Answer 8

• Brand: glucophage

Strength: 500, 850, 1000 mg

Frequency: BID or TID
- Max: 2550 mg/day

Indications:
- Type 2 Diabetes
- Polycystic Ovary Syndrome
- Weight loss

Tips:
- diarrhea, nausea, abdominal pain
- take with food
- titrate dose up weekly
- long term use can cause B12 deficiency

Question 9

Dapaglifozin

Answer 9

Brand: Farxiga

Strength: 5, 10 mg

Frequency: daily

Indications:
- Type 2 Diabetes
- CKD
- heart failure with reduced ejection fraction

Tips:
- UTI
- increased urine output
- decreased blood pressure

Question 10

Liraglutide

Answer 10

Brand: Victoza, Saxenda

Strength: 18mg/3ml

Frequency:
- 0.6 mg daily for 1 week
- titrate up weekly to 1.8 mg daily for diabetes
- titrate up weekly to 3 mg daily for weight management

Indications:
- Type 2 Diabetes
- Weight management

Tips:
- low blood sugar (sweating, nausea, dizziness)
- diarhhea
- nausea
- headache
- rotate injection site